Decellularized adipose matrix hydrogel-based in situ delivery of antagomiR-150-5p for rat abdominal aortic aneurysm therapy

Decellularized adipose matrix hydrogel-based in situ delivery of antagomiR-150-5p for rat abdominal aortic aneurysm therapy

Abdominal aortic aneurysm (AAA) is a progressive aortic disease featured by inflammation, vascular smooth muscle cells (VSMCs) depletion, and elastin degradation. MicroRNAs were related to AAA formation, which bring the approach for precise and targeted drug therapy for AAA. We developed a new strat...

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Bibliographic Details
Main Authors: Xin Chen, Shoushuai Wang, Weijian Hou, Yanhui Zhang, Yapeng Hou, Hao Tong, Xiaoxin Zhang, Yue Liu, Ruoxuan Yang, Xiang Li, Qin Fang, Jun Fan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Abdominal aortic aneurysm
AntagomiR-150-5p
Inflammation
Hydrogel
Decellularized adipose matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004113
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