Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case Reports
Pyoderma gangrenosum (PG) is a rare, chronic, neutrophilic dermatosis characterized by painful ulcers that are often misdiagnosed as wound infections. We report two cases of postsurgical PG following breast surgery: A 46-year-old woman with a non-healing ulcer after a breast biopsy and a 37-year-old...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2025-01-01
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| Series: | European Journal of Breast Health |
| Subjects: | |
| Online Access: | https://www.eurjbreasthealth.com/articles/pyoderma-gangrenosum-a-nightmare-for-breast-surgery-two-case-reports/doi/ejbh.galenos.2024.2024-7-5 |
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| _version_ | 1841556275495698432 |
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| author | Gülşen Akoğlu Murat Demiriz Kerim Bora Yılmaz |
| author_facet | Gülşen Akoğlu Murat Demiriz Kerim Bora Yılmaz |
| author_sort | Gülşen Akoğlu |
| collection | DOAJ |
| description | Pyoderma gangrenosum (PG) is a rare, chronic, neutrophilic dermatosis characterized by painful ulcers that are often misdiagnosed as wound infections. We report two cases of postsurgical PG following breast surgery: A 46-year-old woman with a non-healing ulcer after a breast biopsy and a 37-year-old woman with wound dehiscence after bilateral reduction mammoplasty. Both cases were initially managed with repeated debridements, antibiotics, and wound care without improvement. The diagnosis of PG was made based on the increase in wound size and irregularity. Treatment with oral doxycycline and topical tacrolimus led to favorable healing within four months. Breast surgical tehniques, which aim to achieve aesthetic results using intraglandular flaps, have become an important part of clinical practice in breast surgery. Early diagnosis and appropriate management are crucial in postsurgical PG to avoid misdiagnosis and ineffective treatments that cause patient disfigurement. |
| format | Article |
| id | doaj-art-59bea32f229c418da9d8be6cf092d66c |
| institution | Kabale University |
| issn | 2587-0831 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | European Journal of Breast Health |
| spelling | doaj-art-59bea32f229c418da9d8be6cf092d66c2025-01-07T11:06:37ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312025-01-01211808410.4274/ejbh.galenos.2024.2024-7-5Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case ReportsGülşen Akoğlu0https://orcid.org/0000-0002-9483-6268Murat Demiriz1https://orcid.org/0000-0003-0059-3822Kerim Bora Yılmaz2https://orcid.org/0000-0002-5514-4103Department of Dermatovenereology, Gülhane Training and Research Hospital, University of Health Sciences Turkey, Ankara, TurkeyDepartment of Pathology, Gülhane Training and Research Hospital, University of Health Sciences Turkey, Ankara, TurkeyDepartment of General Surgery, Gülhane Training and Research Hospital, University of Health Sciences Turkey, Ankara, TurkeyPyoderma gangrenosum (PG) is a rare, chronic, neutrophilic dermatosis characterized by painful ulcers that are often misdiagnosed as wound infections. We report two cases of postsurgical PG following breast surgery: A 46-year-old woman with a non-healing ulcer after a breast biopsy and a 37-year-old woman with wound dehiscence after bilateral reduction mammoplasty. Both cases were initially managed with repeated debridements, antibiotics, and wound care without improvement. The diagnosis of PG was made based on the increase in wound size and irregularity. Treatment with oral doxycycline and topical tacrolimus led to favorable healing within four months. Breast surgical tehniques, which aim to achieve aesthetic results using intraglandular flaps, have become an important part of clinical practice in breast surgery. Early diagnosis and appropriate management are crucial in postsurgical PG to avoid misdiagnosis and ineffective treatments that cause patient disfigurement.https://www.eurjbreasthealth.com/articles/pyoderma-gangrenosum-a-nightmare-for-breast-surgery-two-case-reports/doi/ejbh.galenos.2024.2024-7-5pyoderma gangrenosumbreast surgeryreduction mammoplastydoxycyclinetacrolimus |
| spellingShingle | Gülşen Akoğlu Murat Demiriz Kerim Bora Yılmaz Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case Reports European Journal of Breast Health pyoderma gangrenosum breast surgery reduction mammoplasty doxycycline tacrolimus |
| title | Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case Reports |
| title_full | Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case Reports |
| title_fullStr | Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case Reports |
| title_full_unstemmed | Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case Reports |
| title_short | Pyoderma Gangrenosum: A Nightmare for Breast Surgery-Two Case Reports |
| title_sort | pyoderma gangrenosum a nightmare for breast surgery two case reports |
| topic | pyoderma gangrenosum breast surgery reduction mammoplasty doxycycline tacrolimus |
| url | https://www.eurjbreasthealth.com/articles/pyoderma-gangrenosum-a-nightmare-for-breast-surgery-two-case-reports/doi/ejbh.galenos.2024.2024-7-5 |
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