Theoretical investigations on analysis and optimization of freeze drying of pharmaceutical powder using machine learning modeling of temperature distribution

Abstract This study investigates the application of various neural network-based models for predicting temperature distribution in freeze drying process of biopharmaceuticals. For heat-sensitive biopharmaceutical products, freeze drying is preferred to prevent degradation of pharmaceutical compounds...

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Bibliographic Details
Main Authors: Turki Al Hagbani, Jawaher Abdullah Alamoudi, Majed A. Bajaber, Huda Ibrahim Alsayed, Halah Jawad Al-fanhrawi
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-84155-z
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