Fixed-dose combinations in the treatment of hypertension to increase adherence

Despite a wide range of antihypertensive drugs, blood pressure (BP) control often remains unsatisfactory, and every year the number of people with uncontrolled high BP increases. One of the strategies aimed at improving medical adherence is the use of fixed-dose combinations of 2 antihypertensive dr...

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Main Authors: T. E. Morozova, E. O. Samokhina
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2020-12-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/4184
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author T. E. Morozova
E. O. Samokhina
author_facet T. E. Morozova
E. O. Samokhina
author_sort T. E. Morozova
collection DOAJ
description Despite a wide range of antihypertensive drugs, blood pressure (BP) control often remains unsatisfactory, and every year the number of people with uncontrolled high BP increases. One of the strategies aimed at improving medical adherence is the use of fixed-dose combinations of 2 antihypertensive drugs for starting therapy, and, if necessary, 3 drugs. Initiation of therapy with 2 drugs in one tablet is recommended for most patients. A review of algorithms for choosing combinations of antihypertensive drugs in different clinical situations, including in patients with various comorbid conditions, is presented. Simplification of treatment regimens makes it possible to choose the most optimal solutions in various clinical situations, in particular, with stage I-II hypertension, with a combination of hypertension with chronic kidney disease, as well as with a combination of hypertension with coronary artery disease and a number of other diseases.
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institution Kabale University
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publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-58fa0f1e95b44ee1a0aed5d260d724b02025-08-20T03:57:26Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202020-12-01251110.15829/29/1560-4071-2020-41843103Fixed-dose combinations in the treatment of hypertension to increase adherenceT. E. Morozova0E. O. Samokhina1I.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityDespite a wide range of antihypertensive drugs, blood pressure (BP) control often remains unsatisfactory, and every year the number of people with uncontrolled high BP increases. One of the strategies aimed at improving medical adherence is the use of fixed-dose combinations of 2 antihypertensive drugs for starting therapy, and, if necessary, 3 drugs. Initiation of therapy with 2 drugs in one tablet is recommended for most patients. A review of algorithms for choosing combinations of antihypertensive drugs in different clinical situations, including in patients with various comorbid conditions, is presented. Simplification of treatment regimens makes it possible to choose the most optimal solutions in various clinical situations, in particular, with stage I-II hypertension, with a combination of hypertension with chronic kidney disease, as well as with a combination of hypertension with coronary artery disease and a number of other diseases.https://russjcardiol.elpub.ru/jour/article/view/4184hypertensionantihypertensive therapypharmacotherapycombination pharmacotherapyfixed-dose combinationsadherence to treatment
spellingShingle T. E. Morozova
E. O. Samokhina
Fixed-dose combinations in the treatment of hypertension to increase adherence
Российский кардиологический журнал
hypertension
antihypertensive therapy
pharmacotherapy
combination pharmacotherapy
fixed-dose combinations
adherence to treatment
title Fixed-dose combinations in the treatment of hypertension to increase adherence
title_full Fixed-dose combinations in the treatment of hypertension to increase adherence
title_fullStr Fixed-dose combinations in the treatment of hypertension to increase adherence
title_full_unstemmed Fixed-dose combinations in the treatment of hypertension to increase adherence
title_short Fixed-dose combinations in the treatment of hypertension to increase adherence
title_sort fixed dose combinations in the treatment of hypertension to increase adherence
topic hypertension
antihypertensive therapy
pharmacotherapy
combination pharmacotherapy
fixed-dose combinations
adherence to treatment
url https://russjcardiol.elpub.ru/jour/article/view/4184
work_keys_str_mv AT temorozova fixeddosecombinationsinthetreatmentofhypertensiontoincreaseadherence
AT eosamokhina fixeddosecombinationsinthetreatmentofhypertensiontoincreaseadherence