СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR
This study aimed to describe seasonal features of leptospirosis clinical course and laboratory changes in patients with this disease in the Lviv region. Material and Methods. We conducted a retrospective analysis of 395 medical cards of patients with a diagnosis of "Leptospirosis" who w...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Danylo Halytsky Lviv National Medical University
2024-10-01
|
| Series: | Acta Medica Leopoliensia |
| Subjects: | |
| Online Access: | https://amljournal.com/index.php/journal/article/view/395 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841557715348881408 |
|---|---|
| author | Olena Zubach Alexander Zinchuk |
| author_facet | Olena Zubach Alexander Zinchuk |
| author_sort | Olena Zubach |
| collection | DOAJ |
| description | This study aimed to describe seasonal features of leptospirosis clinical course and laboratory changes in patients with this disease in the Lviv region.
Material and Methods. We conducted a retrospective analysis of 395 medical cards of patients with a diagnosis of "Leptospirosis" who were treated at the Lviv Regional Clinical Hospital of Infectious Diseases for a period of 15 years. The results were statistically processed using Fisher's bilateral test.
Results and Discussion. This manuscript analyzes the seasonal features of the clinical course of leptospirosis in the territory of the Lviv region. Despite the highest frequency of leptospirosis cases in the summer-autumn period, the most severe course was observed in spring and winter. This can be explained by a decrease in the body's reactivity during these seasons of the year. It has been established that with leptospirosis, the severity of the disease, as well as the severity of the main symptoms and changes in laboratory parameters can be conventionally expressed in the following order: spring > winter > autumn > summer. Jaundice was observed oftenest in patients with leptospirosis during winter, the main complications of leptospirosis (acute kidney failure, toxic shock syndrome and thrombohemorrhagic syndrome) - during the spring months, and pneumonia - in winter. Among the changes in laboratory data, the following deserve attention: thrombocytopenia and significant anemia are more pronounced in patients during spring, and leukocytosis and hyperazotemia in winter.
Conclusions. The obtained data, which characterize the clinical and laboratory seasonal features of leptospirosis, testify to the fact that the course of leptospirosis is more severe in spring and winter compared to other seasons. |
| format | Article |
| id | doaj-art-58de610e4c3b4ba7bbb7453ef14c27f4 |
| institution | Kabale University |
| issn | 1029-4244 2415-3303 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Danylo Halytsky Lviv National Medical University |
| record_format | Article |
| series | Acta Medica Leopoliensia |
| spelling | doaj-art-58de610e4c3b4ba7bbb7453ef14c27f42025-01-06T10:49:52ZengDanylo Halytsky Lviv National Medical UniversityActa Medica Leopoliensia1029-42442415-33032024-10-01301-292210.25040/aml2024.1-2.009395СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAROlena Zubach0Alexander Zinchuk1Danylo Halytsky Lviv National Medical University, Lviv, Ukraine, Department of Infectious Diseases Danylo Halytsky Lviv National Medical University, Lviv, Ukraine, Department of Infectious Diseases This study aimed to describe seasonal features of leptospirosis clinical course and laboratory changes in patients with this disease in the Lviv region. Material and Methods. We conducted a retrospective analysis of 395 medical cards of patients with a diagnosis of "Leptospirosis" who were treated at the Lviv Regional Clinical Hospital of Infectious Diseases for a period of 15 years. The results were statistically processed using Fisher's bilateral test. Results and Discussion. This manuscript analyzes the seasonal features of the clinical course of leptospirosis in the territory of the Lviv region. Despite the highest frequency of leptospirosis cases in the summer-autumn period, the most severe course was observed in spring and winter. This can be explained by a decrease in the body's reactivity during these seasons of the year. It has been established that with leptospirosis, the severity of the disease, as well as the severity of the main symptoms and changes in laboratory parameters can be conventionally expressed in the following order: spring > winter > autumn > summer. Jaundice was observed oftenest in patients with leptospirosis during winter, the main complications of leptospirosis (acute kidney failure, toxic shock syndrome and thrombohemorrhagic syndrome) - during the spring months, and pneumonia - in winter. Among the changes in laboratory data, the following deserve attention: thrombocytopenia and significant anemia are more pronounced in patients during spring, and leukocytosis and hyperazotemia in winter. Conclusions. The obtained data, which characterize the clinical and laboratory seasonal features of leptospirosis, testify to the fact that the course of leptospirosis is more severe in spring and winter compared to other seasons.https://amljournal.com/index.php/journal/article/view/395leptospirosisclinical pictureseasonalitylaboratory changes |
| spellingShingle | Olena Zubach Alexander Zinchuk СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR Acta Medica Leopoliensia leptospirosis clinical picture seasonality laboratory changes |
| title | СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR |
| title_full | СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR |
| title_fullStr | СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR |
| title_full_unstemmed | СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR |
| title_short | СLINICAL AND LABORATORY FEATURES OF LEPTOSPIROSIS DEPENDING ON THE SEASON OF THE YEAR |
| title_sort | сlinical and laboratory features of leptospirosis depending on the season of the year |
| topic | leptospirosis clinical picture seasonality laboratory changes |
| url | https://amljournal.com/index.php/journal/article/view/395 |
| work_keys_str_mv | AT olenazubach slinicalandlaboratoryfeaturesofleptospirosisdependingontheseasonoftheyear AT alexanderzinchuk slinicalandlaboratoryfeaturesofleptospirosisdependingontheseasonoftheyear |