Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization

Objective This study compared the clinical efficacy of off-pump coronary artery bypass grafting (OPCAB) with percutaneous coronary intervention (PCI) in the treatment of left main coronary artery and/or triple-vessel disease (LM and/or TVD). Methods We retrospectively enrolled 1484 consecutive patie...

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Main Authors: Nan Li, Xin Xiong, Kun Yang, Yijun Xu, Zhiqiang Chen, Peng Liu, Wen Wen, Xiaowei Li, Jin Dong, Shoudong Wei, Durong Chen, Xiaolong Zhang, Dajiang Yuan, Yongzhi Deng
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605241304545
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author Nan Li
Xin Xiong
Kun Yang
Yijun Xu
Zhiqiang Chen
Peng Liu
Wen Wen
Xiaowei Li
Jin Dong
Shoudong Wei
Durong Chen
Xiaolong Zhang
Dajiang Yuan
Yongzhi Deng
author_facet Nan Li
Xin Xiong
Kun Yang
Yijun Xu
Zhiqiang Chen
Peng Liu
Wen Wen
Xiaowei Li
Jin Dong
Shoudong Wei
Durong Chen
Xiaolong Zhang
Dajiang Yuan
Yongzhi Deng
author_sort Nan Li
collection DOAJ
description Objective This study compared the clinical efficacy of off-pump coronary artery bypass grafting (OPCAB) with percutaneous coronary intervention (PCI) in the treatment of left main coronary artery and/or triple-vessel disease (LM and/or TVD). Methods We retrospectively enrolled 1484 consecutive patients with LM and/or TVD in Shanxi Cardiovascular Hospital from January 2015 to December 2022 and divided them into the OPCAB group (n = 583) and the PCI group (with second-generation drug-eluting stents) (n = 901). Propensity score matching was used for 316 equally matched pairs of patients in the groups. The outcomes were all-cause and cardiac mortality, angina recurrence, and major adverse cardiac and cerebrovascular events, which comprised non-lethal myocardial infarction, stroke, and repeat revascularization. Results The mean follow-up was 3.93 years in the OPCAB group and 4.19 years in the PCI group. There were no significant differences in all-cause mortality, cardiac mortality, major adverse cardiac and cerebrovascular events, or non-lethal myocardial infarction between the groups. The incidence of repeat revascularization and angina recurrence was higher in the PCI group than in the OPCAB group. However, the incidence of stroke was higher in the OPCAB group than in the PCI group. Conclusions OPCAB may be a favorable coronary revascularization strategy for LM and/or TVD.
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publisher SAGE Publishing
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spelling doaj-art-588e16d4094d4faba1245c5e78b5a4e42024-12-23T09:04:38ZengSAGE PublishingJournal of International Medical Research1473-23002024-12-015210.1177/03000605241304545Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularizationNan LiXin XiongKun YangYijun XuZhiqiang ChenPeng LiuWen WenXiaowei LiJin DongShoudong WeiDurong ChenXiaolong ZhangDajiang YuanYongzhi DengObjective This study compared the clinical efficacy of off-pump coronary artery bypass grafting (OPCAB) with percutaneous coronary intervention (PCI) in the treatment of left main coronary artery and/or triple-vessel disease (LM and/or TVD). Methods We retrospectively enrolled 1484 consecutive patients with LM and/or TVD in Shanxi Cardiovascular Hospital from January 2015 to December 2022 and divided them into the OPCAB group (n = 583) and the PCI group (with second-generation drug-eluting stents) (n = 901). Propensity score matching was used for 316 equally matched pairs of patients in the groups. The outcomes were all-cause and cardiac mortality, angina recurrence, and major adverse cardiac and cerebrovascular events, which comprised non-lethal myocardial infarction, stroke, and repeat revascularization. Results The mean follow-up was 3.93 years in the OPCAB group and 4.19 years in the PCI group. There were no significant differences in all-cause mortality, cardiac mortality, major adverse cardiac and cerebrovascular events, or non-lethal myocardial infarction between the groups. The incidence of repeat revascularization and angina recurrence was higher in the PCI group than in the OPCAB group. However, the incidence of stroke was higher in the OPCAB group than in the PCI group. Conclusions OPCAB may be a favorable coronary revascularization strategy for LM and/or TVD.https://doi.org/10.1177/03000605241304545
spellingShingle Nan Li
Xin Xiong
Kun Yang
Yijun Xu
Zhiqiang Chen
Peng Liu
Wen Wen
Xiaowei Li
Jin Dong
Shoudong Wei
Durong Chen
Xiaolong Zhang
Dajiang Yuan
Yongzhi Deng
Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization
Journal of International Medical Research
title Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization
title_full Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization
title_fullStr Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization
title_full_unstemmed Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization
title_short Off-pump coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for coronary artery revascularization
title_sort off pump coronary artery bypass grafting versus percutaneous coronary intervention with second generation drug eluting stents for coronary artery revascularization
url https://doi.org/10.1177/03000605241304545
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