Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers

Artificial intelligence (AI) has become a powerful tool in biochemistry, greatly enhancing research capabilities by enabling the analysis of complex datasets, predicting molecular interactions, and accelerating drug discovery. As AI continues to evolve, its applications in biochemistry are poised t...

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Main Author: Mohammed Abdul Lateef Junaid
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2025-01-01
Series:Biomolecules & Biomedicine
Subjects:
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/11537
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author Mohammed Abdul Lateef Junaid
author_facet Mohammed Abdul Lateef Junaid
author_sort Mohammed Abdul Lateef Junaid
collection DOAJ
description Artificial intelligence (AI) has become a powerful tool in biochemistry, greatly enhancing research capabilities by enabling the analysis of complex datasets, predicting molecular interactions, and accelerating drug discovery. As AI continues to evolve, its applications in biochemistry are poised to expand, revolutionizing both theoretical and applied research. This review explores current and potential AI applications in biochemistry, with a focus on data analysis, molecular modeling, enzyme engineering, and metabolic pathway studies. Key AI techniques—such as machine learning algorithms, natural language processing, and AI-based molecular modeling—are discussed. The review also highlights emerging research areas benefiting from AI, including personalized medicine and synthetic biology. The methodology involves an extensive analysis of existing literature, particularly peer-reviewed studies on AI applications in biochemistry. AI-driven tools like AlphaFold, which have significantly advanced protein structure prediction, are evaluated alongside AI’s role in expediting drug discovery. The review also addresses challenges such as data quality, model interpretability, and ethical considerations. Results indicate that AI has expanded the scope of biochemical research by facilitating large-scale data analysis, enhancing molecular simulations, and opening new avenues of inquiry. However, challenges remain, particularly in data handling and ethical concerns. In conclusion, AI is transforming biochemistry by driving innovation and expanding research possibilities. Future advancements in AI algorithms, interdisciplinary collaboration, and integration with automated techniques will be crucial to fully unlocking AI’s potential in advancing biochemical research.
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spelling doaj-art-585fb49b04754e559d925660862444f32025-01-16T16:40:12ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2025-01-0110.17305/bb.2024.11537Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiersMohammed Abdul Lateef Junaid0Department of Basic Medical Sciences, College of Medicine, Majmaah University, Al Majmaah, Kingdom of Saudi Arabia Artificial intelligence (AI) has become a powerful tool in biochemistry, greatly enhancing research capabilities by enabling the analysis of complex datasets, predicting molecular interactions, and accelerating drug discovery. As AI continues to evolve, its applications in biochemistry are poised to expand, revolutionizing both theoretical and applied research. This review explores current and potential AI applications in biochemistry, with a focus on data analysis, molecular modeling, enzyme engineering, and metabolic pathway studies. Key AI techniques—such as machine learning algorithms, natural language processing, and AI-based molecular modeling—are discussed. The review also highlights emerging research areas benefiting from AI, including personalized medicine and synthetic biology. The methodology involves an extensive analysis of existing literature, particularly peer-reviewed studies on AI applications in biochemistry. AI-driven tools like AlphaFold, which have significantly advanced protein structure prediction, are evaluated alongside AI’s role in expediting drug discovery. The review also addresses challenges such as data quality, model interpretability, and ethical considerations. Results indicate that AI has expanded the scope of biochemical research by facilitating large-scale data analysis, enhancing molecular simulations, and opening new avenues of inquiry. However, challenges remain, particularly in data handling and ethical concerns. In conclusion, AI is transforming biochemistry by driving innovation and expanding research possibilities. Future advancements in AI algorithms, interdisciplinary collaboration, and integration with automated techniques will be crucial to fully unlocking AI’s potential in advancing biochemical research. https://www.bjbms.org/ojs/index.php/bjbms/article/view/11537Artificial intelligenceAIbiochemistrymachine learningmolecular modelingdrug discovery
spellingShingle Mohammed Abdul Lateef Junaid
Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers
Biomolecules & Biomedicine
Artificial intelligence
AI
biochemistry
machine learning
molecular modeling
drug discovery
title Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers
title_full Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers
title_fullStr Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers
title_full_unstemmed Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers
title_short Artificial intelligence driven innovations in biochemistry: A review of emerging research frontiers
title_sort artificial intelligence driven innovations in biochemistry a review of emerging research frontiers
topic Artificial intelligence
AI
biochemistry
machine learning
molecular modeling
drug discovery
url https://www.bjbms.org/ojs/index.php/bjbms/article/view/11537
work_keys_str_mv AT mohammedabdullateefjunaid artificialintelligencedriveninnovationsinbiochemistryareviewofemergingresearchfrontiers