COVID-19–associated central nervous system mucormycosis

Mucormycosis is a life-threatening infection caused by fungi of the order Mucorales. Central nervous system (CNS) mucormycosis is usually an extension of the infection from the sinuses to the eyes and brain. CNS mucormycosis arises from an adjacent paranasal sinus infection (rhinocerebral) by direct...

Full description

Saved in:
Bibliographic Details
Main Authors: Anjali Mishra, Dinesh Mohan Chaudhari, Pushpendra Nath Renjen
Format: Article
Language:English
Published: SAGE Publishing 2021-01-01
Series:Apollo Medicine
Subjects:
Online Access:http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2021;volume=18;issue=3;spage=192;epage=195;aulast=Mishra
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846096330703765504
author Anjali Mishra
Dinesh Mohan Chaudhari
Pushpendra Nath Renjen
author_facet Anjali Mishra
Dinesh Mohan Chaudhari
Pushpendra Nath Renjen
author_sort Anjali Mishra
collection DOAJ
description Mucormycosis is a life-threatening infection caused by fungi of the order Mucorales. Central nervous system (CNS) mucormycosis is usually an extension of the infection from the sinuses to the eyes and brain. CNS mucormycosis arises from an adjacent paranasal sinus infection (rhinocerebral) by direct extension or hematogenous dissemination from the lungs, but isolated CNS mucormycosis is a rare presentation. During an episode of fungemia, seeding may occur in brain tissue, leading to this infection. The most common clinical presentation of mucormycosis is rhino-orbital-cerebral infection, which is presumed to start with inhalation of spores into the paranasal sinuses of a susceptible host. In this article, we emphasize on the COVID-19–associated mucormycosis, particularly the involvement of CNS.
format Article
id doaj-art-5802bef2ff81447190b0e66b1eee096d
institution Kabale University
issn 0976-0016
2213-3682
language English
publishDate 2021-01-01
publisher SAGE Publishing
record_format Article
series Apollo Medicine
spelling doaj-art-5802bef2ff81447190b0e66b1eee096d2025-01-02T07:13:38ZengSAGE PublishingApollo Medicine0976-00162213-36822021-01-0118319219510.4103/am.am_84_21COVID-19–associated central nervous system mucormycosisAnjali MishraDinesh Mohan ChaudhariPushpendra Nath RenjenMucormycosis is a life-threatening infection caused by fungi of the order Mucorales. Central nervous system (CNS) mucormycosis is usually an extension of the infection from the sinuses to the eyes and brain. CNS mucormycosis arises from an adjacent paranasal sinus infection (rhinocerebral) by direct extension or hematogenous dissemination from the lungs, but isolated CNS mucormycosis is a rare presentation. During an episode of fungemia, seeding may occur in brain tissue, leading to this infection. The most common clinical presentation of mucormycosis is rhino-orbital-cerebral infection, which is presumed to start with inhalation of spores into the paranasal sinuses of a susceptible host. In this article, we emphasize on the COVID-19–associated mucormycosis, particularly the involvement of CNS.http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2021;volume=18;issue=3;spage=192;epage=195;aulast=Mishracovid-19–associated mucormycosiscentral nervous systemcoronavirus disease 2019fungal infectionmucormycosisrhino-orbital-cerebral mucormycosis
spellingShingle Anjali Mishra
Dinesh Mohan Chaudhari
Pushpendra Nath Renjen
COVID-19–associated central nervous system mucormycosis
Apollo Medicine
covid-19–associated mucormycosis
central nervous system
coronavirus disease 2019
fungal infection
mucormycosis
rhino-orbital-cerebral mucormycosis
title COVID-19–associated central nervous system mucormycosis
title_full COVID-19–associated central nervous system mucormycosis
title_fullStr COVID-19–associated central nervous system mucormycosis
title_full_unstemmed COVID-19–associated central nervous system mucormycosis
title_short COVID-19–associated central nervous system mucormycosis
title_sort covid 19 associated central nervous system mucormycosis
topic covid-19–associated mucormycosis
central nervous system
coronavirus disease 2019
fungal infection
mucormycosis
rhino-orbital-cerebral mucormycosis
url http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2021;volume=18;issue=3;spage=192;epage=195;aulast=Mishra
work_keys_str_mv AT anjalimishra covid19associatedcentralnervoussystemmucormycosis
AT dineshmohanchaudhari covid19associatedcentralnervoussystemmucormycosis
AT pushpendranathrenjen covid19associatedcentralnervoussystemmucormycosis