Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province
Abstract Background and aims Cholecystectomy is one of the most common surgical procedures for the treatment of diseases associated with gallstones, and the incidence of post-cholecystectomy diarrhea (PCD) has attracted attention in recent years. The aim of this study was to assess the prevalence of...
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2025-04-01
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| Series: | BMC Gastroenterology |
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| Online Access: | https://doi.org/10.1186/s12876-025-03810-5 |
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| author | Fengjiao Mao Daya Zhang Xianfeng Huang Da Li Wenrui Chen Fan Zeng Chen Chen Shimei Huang Yanting Lv Yuliang Huang Runyu Chen Ying Mo Qiuli Nie Shuo Zhou Xiaodong Zhang Qicen Yao Yiping Du Bo Ran Yan Tan Na Liu Yunqian Xie Feihu Bai |
| author_facet | Fengjiao Mao Daya Zhang Xianfeng Huang Da Li Wenrui Chen Fan Zeng Chen Chen Shimei Huang Yanting Lv Yuliang Huang Runyu Chen Ying Mo Qiuli Nie Shuo Zhou Xiaodong Zhang Qicen Yao Yiping Du Bo Ran Yan Tan Na Liu Yunqian Xie Feihu Bai |
| author_sort | Fengjiao Mao |
| collection | DOAJ |
| description | Abstract Background and aims Cholecystectomy is one of the most common surgical procedures for the treatment of diseases associated with gallstones, and the incidence of post-cholecystectomy diarrhea (PCD) has attracted attention in recent years. The aim of this study was to assess the prevalence of PCD in patients with gallstones and to analyze the factors influencing it. Methods Between August 2022 and December 2024, there were 3385 cases of gallstones diagnosed by abdominal ultrasound or CT examination and laparoscopic cholecystectomy in tertiary hospitals in Hainan Province. All participants in this study were followed up by telephone within 1 year postoperatively and by telephone survey using a standardized questionnaire. The incidence of PCD was calculated, and the relevant components of the follow-up were analyzed by one-way and multifactorial logistic regression using SPSS 26.0 statistical software. Results Four hundred seventy-nine patients (14.2%) developed PCD after undergoing laparoscopic cholecystectomy. Univariate analysis showed that age, BMI, dietary patterns, history of diabetes, alcohol consumption, gallstones and fatty liver disease were associated with the development of PCD ( P < 0.05). Binary logistic regression analysis showed that age (OR = 0.532, P = 0.010), BMI (OR = 40.615, P < 0.001), dietary patterns (OR = 0.635, P = 0.013), and history of diabetes (OR = 0.263, P < 0.001) were independent risk factors. Conclusion The incidence of PCD in Hainan Province is 14.2%. Over 50 years old, BMI, dietary pattern and history of diabetes were independent risk factors for the occurrence of PCD. |
| format | Article |
| id | doaj-art-57fe90f20a1f4beaba7d16b5d5cdc9a0 |
| institution | DOAJ |
| issn | 1471-230X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj-art-57fe90f20a1f4beaba7d16b5d5cdc9a02025-08-20T03:06:57ZengBMCBMC Gastroenterology1471-230X2025-04-012511710.1186/s12876-025-03810-5Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan ProvinceFengjiao Mao0Daya Zhang1Xianfeng Huang2Da Li3Wenrui Chen4Fan Zeng5Chen Chen6Shimei Huang7Yanting Lv8Yuliang Huang9Runyu Chen10Ying Mo11Qiuli Nie12Shuo Zhou13Xiaodong Zhang14Qicen Yao15Yiping Du16Bo Ran17Yan Tan18Na Liu19Yunqian Xie20Feihu Bai21The Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityThe Second School of Clinical Medicine, Hainan Medical UniversityDepartment of Rheumatology and Immunology, The Second Affiliated Hospital of Hainan Medical UniversityCardiovascular Surgery, The Second Affiliated Hospital of Hainan Medical UniversityHepatobiliary Surgery, The Second Affiliated Hospital of Hainan Medical UniversityThe First School of Clinical Medicine, Hainan Medical UniversityAffiliated Hospital of Hainan Medical University HaikouDepartment of Gastroenterology, The Second Affiliated Hospital of Hainan Medical UniversityDepartment of Gastroenterology, The Second Affiliated Hospital of Hainan Medical UniversityAbstract Background and aims Cholecystectomy is one of the most common surgical procedures for the treatment of diseases associated with gallstones, and the incidence of post-cholecystectomy diarrhea (PCD) has attracted attention in recent years. The aim of this study was to assess the prevalence of PCD in patients with gallstones and to analyze the factors influencing it. Methods Between August 2022 and December 2024, there were 3385 cases of gallstones diagnosed by abdominal ultrasound or CT examination and laparoscopic cholecystectomy in tertiary hospitals in Hainan Province. All participants in this study were followed up by telephone within 1 year postoperatively and by telephone survey using a standardized questionnaire. The incidence of PCD was calculated, and the relevant components of the follow-up were analyzed by one-way and multifactorial logistic regression using SPSS 26.0 statistical software. Results Four hundred seventy-nine patients (14.2%) developed PCD after undergoing laparoscopic cholecystectomy. Univariate analysis showed that age, BMI, dietary patterns, history of diabetes, alcohol consumption, gallstones and fatty liver disease were associated with the development of PCD ( P < 0.05). Binary logistic regression analysis showed that age (OR = 0.532, P = 0.010), BMI (OR = 40.615, P < 0.001), dietary patterns (OR = 0.635, P = 0.013), and history of diabetes (OR = 0.263, P < 0.001) were independent risk factors. Conclusion The incidence of PCD in Hainan Province is 14.2%. Over 50 years old, BMI, dietary pattern and history of diabetes were independent risk factors for the occurrence of PCD.https://doi.org/10.1186/s12876-025-03810-5Laparoscopic cholecystectomyGallstonesMorbidityRisk factorsPost-cholecystectomy diarrhea |
| spellingShingle | Fengjiao Mao Daya Zhang Xianfeng Huang Da Li Wenrui Chen Fan Zeng Chen Chen Shimei Huang Yanting Lv Yuliang Huang Runyu Chen Ying Mo Qiuli Nie Shuo Zhou Xiaodong Zhang Qicen Yao Yiping Du Bo Ran Yan Tan Na Liu Yunqian Xie Feihu Bai Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province BMC Gastroenterology Laparoscopic cholecystectomy Gallstones Morbidity Risk factors Post-cholecystectomy diarrhea |
| title | Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province |
| title_full | Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province |
| title_fullStr | Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province |
| title_full_unstemmed | Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province |
| title_short | Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province |
| title_sort | analysis of the incidence of post cholecystectomy diarrhea and its influencing factors in hainan province |
| topic | Laparoscopic cholecystectomy Gallstones Morbidity Risk factors Post-cholecystectomy diarrhea |
| url | https://doi.org/10.1186/s12876-025-03810-5 |
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