A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten

Gluten, known as the major allergen in wheat, has gained increasing concerns in industrialized countries, resulting in an urgent need for accurate, high-sensitive, and on-site detection of wheat gluten in complex food systems. Herein, we proposed a silver nanoparticles (AgNPs)/metal-organic framewor...

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Bibliographic Details
Main Authors: Linglin Fu, Yanzhuo Du, Jinru Zhou, Huan Li, Minzi Wang, Yanbo Wang
Format: Article
Language:English
Published: Tsinghua University Press 2024-03-01
Series:Food Science and Human Wellness
Subjects:
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2022.9250057
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Summary:Gluten, known as the major allergen in wheat, has gained increasing concerns in industrialized countries, resulting in an urgent need for accurate, high-sensitive, and on-site detection of wheat gluten in complex food systems. Herein, we proposed a silver nanoparticles (AgNPs)/metal-organic framework (MOF) substrate-based surface-enhanced Raman scattering (SERS) sensor for the high-sensitive on-site detection of wheat gluten. The detection occurred on the newly in-situ synthesized AgNPs/MOF-modified SERS substrate, providing an enhancement factor (EF) of 1.89 × 105. Benefitting from the signal amplification function of AgNPs/MOF and the superiority of SERS, this sensor represented high sensitivity performance and a wide detection range from 1 × 10-15 mol/L to 2 × 10-6 mol/L with a detection limit of 1.16 × 10-16 mol/L, which allowed monitoring the trace of wheat gluten in complex food system without matrix interference. This reliable sandwich SERS sensor may provide a promising platform for high-sensitive, accurate, and on-site detection of allergens in the field of food safety.
ISSN:2213-4530