Fatal food anaphylaxis in adults and children
Abstract Anaphylaxis is a life-threatening reaction characterized by the acute onset of symptoms involving different organ systems and requiring immediate medical intervention. The incidence of fatal food anaphylaxis is 0.03 to 0.3 million/people/year. Most fatal food-induced anaphylaxis occurs in t...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | Italian Journal of Pediatrics |
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| Online Access: | https://doi.org/10.1186/s13052-024-01608-x |
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| author | Elio Novembre Mariannita Gelsomino Lucia Liotti Simona Barni Francesca Mori Mattia Giovannini Carla Mastrorilli Luca Pecoraro Francesca Saretta Riccardo Castagnoli Stefania Arasi Lucia Caminiti Angela Klain Michele Miraglia del Giudice |
| author_facet | Elio Novembre Mariannita Gelsomino Lucia Liotti Simona Barni Francesca Mori Mattia Giovannini Carla Mastrorilli Luca Pecoraro Francesca Saretta Riccardo Castagnoli Stefania Arasi Lucia Caminiti Angela Klain Michele Miraglia del Giudice |
| author_sort | Elio Novembre |
| collection | DOAJ |
| description | Abstract Anaphylaxis is a life-threatening reaction characterized by the acute onset of symptoms involving different organ systems and requiring immediate medical intervention. The incidence of fatal food anaphylaxis is 0.03 to 0.3 million/people/year. Most fatal food-induced anaphylaxis occurs in the second and third decades of life. The identified risk factors include the delayed use of epinephrine, the presence of asthma, the use of recreational drugs (alcohol, nicotine, cannabis, etc.), and an upright position. In the United Kingdom (UK) and Canada, the reported leading causal foods are peanuts and tree nuts. In Italy, milk seems to be the most common cause of fatal anaphylaxis in children < 18 years. Fatal food anaphylaxis in Italian children and adolescents almost always occurs outside and is characterized by cardiorespiratory arrest; auto-injectable adrenaline intramuscular was available in few cases. Mortality from food anaphylaxis, especially in children, is a very rare event with stable incidence, but its risk deeply impacts the quality of life of patients with food allergy and their families. Prevention of fatal food anaphylaxis must involve patients and their families, as well as the general public, public authorities, and patients’ associations. |
| format | Article |
| id | doaj-art-56b64157310d4f1eab59c47d02cee9da |
| institution | Kabale University |
| issn | 1824-7288 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj-art-56b64157310d4f1eab59c47d02cee9da2024-11-10T12:35:36ZengBMCItalian Journal of Pediatrics1824-72882024-03-0150111110.1186/s13052-024-01608-xFatal food anaphylaxis in adults and childrenElio Novembre0Mariannita Gelsomino1Lucia Liotti2Simona Barni3Francesca Mori4Mattia Giovannini5Carla Mastrorilli6Luca Pecoraro7Francesca Saretta8Riccardo Castagnoli9Stefania Arasi10Lucia Caminiti11Angela Klain12Michele Miraglia del Giudice13Allergy Unit, Meyer Children’s Hospital IRCCSDepartment of Life Sciences and Public Health, Pediatric Allergy Unit, University Foundation Policlinico Gemelli IRCCS Catholic University of the Sacred HeartDepartment of Mother and Child Health, Pediatric Unit, Salesi Children’s HospitalAllergy Unit, Meyer Children’s Hospital IRCCSAllergy Unit, Meyer Children’s Hospital IRCCSAllergy Unit, Meyer Children’s Hospital IRCCSPediatric Hospital Giovanni XXIII, Pediatric and Emergency Department, AOU Policlinic of BariDepartment of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Unit, University of VeronaPediatric Department, Latisana-Palmanova Hospital, Azienda Sanitaria Universitaria Friuli CentraleDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of PaviaTranslational Research in Pediatric Specialties Area, Division of Allergy, Bambino Gesù Children’s Hospital, IRCCSDepartment of Pediatrics, Allergy Unit, AOU Policlinico Gaetano MartinoDepartment of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”Abstract Anaphylaxis is a life-threatening reaction characterized by the acute onset of symptoms involving different organ systems and requiring immediate medical intervention. The incidence of fatal food anaphylaxis is 0.03 to 0.3 million/people/year. Most fatal food-induced anaphylaxis occurs in the second and third decades of life. The identified risk factors include the delayed use of epinephrine, the presence of asthma, the use of recreational drugs (alcohol, nicotine, cannabis, etc.), and an upright position. In the United Kingdom (UK) and Canada, the reported leading causal foods are peanuts and tree nuts. In Italy, milk seems to be the most common cause of fatal anaphylaxis in children < 18 years. Fatal food anaphylaxis in Italian children and adolescents almost always occurs outside and is characterized by cardiorespiratory arrest; auto-injectable adrenaline intramuscular was available in few cases. Mortality from food anaphylaxis, especially in children, is a very rare event with stable incidence, but its risk deeply impacts the quality of life of patients with food allergy and their families. Prevention of fatal food anaphylaxis must involve patients and their families, as well as the general public, public authorities, and patients’ associations.https://doi.org/10.1186/s13052-024-01608-xFatal anaphylaxisFood allergyDrug allergyPreventionEpinephrine |
| spellingShingle | Elio Novembre Mariannita Gelsomino Lucia Liotti Simona Barni Francesca Mori Mattia Giovannini Carla Mastrorilli Luca Pecoraro Francesca Saretta Riccardo Castagnoli Stefania Arasi Lucia Caminiti Angela Klain Michele Miraglia del Giudice Fatal food anaphylaxis in adults and children Italian Journal of Pediatrics Fatal anaphylaxis Food allergy Drug allergy Prevention Epinephrine |
| title | Fatal food anaphylaxis in adults and children |
| title_full | Fatal food anaphylaxis in adults and children |
| title_fullStr | Fatal food anaphylaxis in adults and children |
| title_full_unstemmed | Fatal food anaphylaxis in adults and children |
| title_short | Fatal food anaphylaxis in adults and children |
| title_sort | fatal food anaphylaxis in adults and children |
| topic | Fatal anaphylaxis Food allergy Drug allergy Prevention Epinephrine |
| url | https://doi.org/10.1186/s13052-024-01608-x |
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