BRD8 Guards the Pluripotent State by Sensing and Maintaining Histone Acetylation

BRD8 Guards the Pluripotent State by Sensing and Maintaining Histone Acetylation

Abstract Epigenetic control of cell fates is a critical determinant to maintain cell type stability and permit differentiation during embryonic development. However, the epigenetic control mechanisms are not well understood. Here, it is shown that the histone acetyltransferase reader protein BRD8 im...

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Bibliographic Details
Main Authors: Li Sun, Xiuling Fu, Zhen Xiao, Gang Ma, Yibin Zhou, Haoqing Hu, Liyang Shi, Dongwei Li, Ralf Jauch, Andrew Paul Hutchins
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
chromatin
epigenetics
histone acetylation
pluripotent stem cells
Online Access:https://doi.org/10.1002/advs.202409160
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