Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review
There is a high prevalence of heart failure (HF) worldwide, which has significant consequences for healthcare costs, patient death and quality of life. Therefore, there has been much focus on finding and using biomarkers for early diagnosis, prognostication and therapy of HF. This overview of the re...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Radcliffe Medical Media
2024-06-01
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| Series: | Cardiac Failure Review |
| Online Access: | https://www.cfrjournal.com/articleindex/cfr.2023.24 |
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| _version_ | 1846122320251322368 |
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| author | Moza A Alzaabi Amin Abdelsalam Majid Alhammadi Hasan Bani Hani Ali Almheiri Nadya Al Matrooshi Khaled Al Zaman |
| author_facet | Moza A Alzaabi Amin Abdelsalam Majid Alhammadi Hasan Bani Hani Ali Almheiri Nadya Al Matrooshi Khaled Al Zaman |
| author_sort | Moza A Alzaabi |
| collection | DOAJ |
| description | There is a high prevalence of heart failure (HF) worldwide, which has significant consequences for healthcare costs, patient death and quality of life. Therefore, there has been much focus on finding and using biomarkers for early diagnosis, prognostication and therapy of HF. This overview of the research presents a thorough examination of the current state of HF biomarkers and their many uses. Their function in diagnosing HF, gauging its severity and monitoring its response to therapy are all discussed. Particularly promising in HF diagnosis and risk stratification are the cardiac-specific biomarkers, B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide. Markers of oxidative stress, extracellular matrix, renal function, inflammation and cardiac peptides have shown promise in evaluating HF severity and prognosis. MicroRNAs and insulin-like growth factor are two emerging biomarkers that have shown potential in helping with HF diagnosis and prognosis. |
| format | Article |
| id | doaj-art-569ad425721f48c8a4122a3ba4bfe931 |
| institution | Kabale University |
| issn | 2057-7540 2057-7559 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Cardiac Failure Review |
| spelling | doaj-art-569ad425721f48c8a4122a3ba4bfe9312024-12-14T16:05:03ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592024-06-011010.15420/cfr.2023.24Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive ReviewMoza A Alzaabi0Amin Abdelsalam1Majid Alhammadi2Hasan Bani Hani3Ali Almheiri4Nadya Al Matrooshi5Khaled Al Zaman6Cardiothoracic Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab EmiratesDepartment of Cardiology, Al Qassemi Hospital, Sharjah, United Arab EmiratesCollege of Medicine, University of Sharjah, Sharjah, United Arab EmiratesCollege of Medicine, University of Sharjah, Sharjah, United Arab EmiratesCollege of Medicine, University of Sharjah, Sharjah, United Arab EmiratesCardiothoracic Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab EmiratesCardiothoracic Surgery, Heart, Vascular & Thoracic Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; College of Medicine, University of Sharjah, Sharjah, United Arab EmiratesThere is a high prevalence of heart failure (HF) worldwide, which has significant consequences for healthcare costs, patient death and quality of life. Therefore, there has been much focus on finding and using biomarkers for early diagnosis, prognostication and therapy of HF. This overview of the research presents a thorough examination of the current state of HF biomarkers and their many uses. Their function in diagnosing HF, gauging its severity and monitoring its response to therapy are all discussed. Particularly promising in HF diagnosis and risk stratification are the cardiac-specific biomarkers, B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide. Markers of oxidative stress, extracellular matrix, renal function, inflammation and cardiac peptides have shown promise in evaluating HF severity and prognosis. MicroRNAs and insulin-like growth factor are two emerging biomarkers that have shown potential in helping with HF diagnosis and prognosis.https://www.cfrjournal.com/articleindex/cfr.2023.24 |
| spellingShingle | Moza A Alzaabi Amin Abdelsalam Majid Alhammadi Hasan Bani Hani Ali Almheiri Nadya Al Matrooshi Khaled Al Zaman Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review Cardiac Failure Review |
| title | Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review |
| title_full | Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review |
| title_fullStr | Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review |
| title_full_unstemmed | Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review |
| title_short | Evaluating Biomarkers as Tools for Early Detection and Prognosis of Heart Failure: A Comprehensive Review |
| title_sort | evaluating biomarkers as tools for early detection and prognosis of heart failure a comprehensive review |
| url | https://www.cfrjournal.com/articleindex/cfr.2023.24 |
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