The Relationship Between the Triglyceride-Glucose Index and Cryptogenic Stroke in Patients with Patent Foramen Ovale
Objective This study aimed to investigate the association between the triglyceride-glucose (TyG) index and cryptogenic stroke (CS) in patients diagnosed with patent foramen ovale (PFO) using transesophageal echocardiography (TEE). Methods A retrospective, single-center study was conducted at a terti...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-11-01
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| Series: | Clinical and Applied Thrombosis/Hemostasis |
| Online Access: | https://doi.org/10.1177/10760296241301411 |
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| author | Fatma Esin MD Hüseyin Sefa Ince MD Semih Aktürk MD Fahrettin Tugrul Citekci MD Aykan Celik MD Ugur Kocabas MD Tuncay Kiris MD Mustafa Karaca MD |
| author_facet | Fatma Esin MD Hüseyin Sefa Ince MD Semih Aktürk MD Fahrettin Tugrul Citekci MD Aykan Celik MD Ugur Kocabas MD Tuncay Kiris MD Mustafa Karaca MD |
| author_sort | Fatma Esin MD |
| collection | DOAJ |
| description | Objective This study aimed to investigate the association between the triglyceride-glucose (TyG) index and cryptogenic stroke (CS) in patients diagnosed with patent foramen ovale (PFO) using transesophageal echocardiography (TEE). Methods A retrospective, single-center study was conducted at a tertiary education and research hospital from January 2015 to December 2023. The study population included 1017 consecutive patients with sinus rhythm diagnosed with PFO, of whom 210 had CS. The TyG Index was calculated using triglyceride and fasting glucose levels. Results Patients with CS were older (47.53 ± 12.34 years) compared to control group (44.40 ± 17.82 years, p = .005). The proportion of males was higher in the CS group (56.2%) compared to the control group (48.3%, p = .042). Laboratory findings revealed higher TyG Index (8.87 ± 0.51 vs 8.63 ± 0.55, p < .001) in patients with CS. TyG Index was an independent predictor of CS in patients with PFO (OR: 2.832, 95%CI: 1.979-4.053 p < .001). Conclusion Elevated TyG Index levels was associated with CS in patients with PFO. The TyG index may serve as a useful biomarker for assessing CS risk in this population. |
| format | Article |
| id | doaj-art-566d8cbcbede45219e92f4e10e75c750 |
| institution | Kabale University |
| issn | 1938-2723 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical and Applied Thrombosis/Hemostasis |
| spelling | doaj-art-566d8cbcbede45219e92f4e10e75c7502024-12-11T07:03:20ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232024-11-013010.1177/10760296241301411The Relationship Between the Triglyceride-Glucose Index and Cryptogenic Stroke in Patients with Patent Foramen OvaleFatma Esin MDHüseyin Sefa Ince MDSemih Aktürk MD Fahrettin Tugrul Citekci MDAykan Celik MDUgur Kocabas MD Tuncay Kiris MDMustafa Karaca MDObjective This study aimed to investigate the association between the triglyceride-glucose (TyG) index and cryptogenic stroke (CS) in patients diagnosed with patent foramen ovale (PFO) using transesophageal echocardiography (TEE). Methods A retrospective, single-center study was conducted at a tertiary education and research hospital from January 2015 to December 2023. The study population included 1017 consecutive patients with sinus rhythm diagnosed with PFO, of whom 210 had CS. The TyG Index was calculated using triglyceride and fasting glucose levels. Results Patients with CS were older (47.53 ± 12.34 years) compared to control group (44.40 ± 17.82 years, p = .005). The proportion of males was higher in the CS group (56.2%) compared to the control group (48.3%, p = .042). Laboratory findings revealed higher TyG Index (8.87 ± 0.51 vs 8.63 ± 0.55, p < .001) in patients with CS. TyG Index was an independent predictor of CS in patients with PFO (OR: 2.832, 95%CI: 1.979-4.053 p < .001). Conclusion Elevated TyG Index levels was associated with CS in patients with PFO. The TyG index may serve as a useful biomarker for assessing CS risk in this population.https://doi.org/10.1177/10760296241301411 |
| spellingShingle | Fatma Esin MD Hüseyin Sefa Ince MD Semih Aktürk MD Fahrettin Tugrul Citekci MD Aykan Celik MD Ugur Kocabas MD Tuncay Kiris MD Mustafa Karaca MD The Relationship Between the Triglyceride-Glucose Index and Cryptogenic Stroke in Patients with Patent Foramen Ovale Clinical and Applied Thrombosis/Hemostasis |
| title | The Relationship Between the
Triglyceride-Glucose Index and Cryptogenic Stroke in Patients
with Patent Foramen Ovale |
| title_full | The Relationship Between the
Triglyceride-Glucose Index and Cryptogenic Stroke in Patients
with Patent Foramen Ovale |
| title_fullStr | The Relationship Between the
Triglyceride-Glucose Index and Cryptogenic Stroke in Patients
with Patent Foramen Ovale |
| title_full_unstemmed | The Relationship Between the
Triglyceride-Glucose Index and Cryptogenic Stroke in Patients
with Patent Foramen Ovale |
| title_short | The Relationship Between the
Triglyceride-Glucose Index and Cryptogenic Stroke in Patients
with Patent Foramen Ovale |
| title_sort | relationship between the triglyceride glucose index and cryptogenic stroke in patients with patent foramen ovale |
| url | https://doi.org/10.1177/10760296241301411 |
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