Characteristics of successful expansion of tumor-infiltrating lymphocytes from colorectal cancer liver metastasis

Characteristics of successful expansion of tumor-infiltrating lymphocytes from colorectal cancer liver metastasis

Abstract Adoptive cell therapy (ACT) utilizing tumor-infiltrating lymphocytes (TILs) has emerged as a successful treatment modality for various malignancies. However, TILs cultured from colorectal cancer (CRC) liver metastasis remain underexplored. Fifteen CRC liver metastasis tissues underwent init...

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Bibliographic Details
Main Authors: Jina Baek, Gyuheon Choi, GunHee Lee, Hyun Lee, Gyungyub Gong, Hye Seon Park, Chae-Lyul Lim, Joo Young Kim, Hee Jin Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Liver metastasis
Tumor-infiltrating lymphocytes
Adoptive cell therapy
Online Access:https://doi.org/10.1038/s41598-025-85892-5
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