Recombinant pseudorabies virus expressing the consensus VP2 protein of porcine parvovirus 1 (PPV1) protects pigs against pseudorabies virus and PPV1

Recombinant pseudorabies virus expressing the consensus VP2 protein of porcine parvovirus 1 (PPV1) protects pigs against pseudorabies virus and PPV1

Abstract Pseudorabies virus (PRV) and porcine parvovirus type 1 (PPV1) are major pathogens that cause reproductive disorders in sows, and mixed infections are frequently detected on pig farms. In this study, a recombinant PRV (rPRV-VP2) based on a PRV variant (HLJ8) was constructed to express the PP...

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Main Authors: Xiaoxiao Tian, Haojie Wang, Hao Song, Ziyi Wei, Xulong Zhu, Guoqing Liu, Mingxia Sun, Xinyi Huang, Meng Chen, Yandong Tang, Haiwei Wang, Yongbo Yang, Tongqing An
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Veterinary Research
Subjects:
PRV variant
PPV1
consensus VP2
genetic stability
chimeric viral vector vaccine
Online Access:https://doi.org/10.1186/s13567-025-01592-y
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https://doi.org/10.1186/s13567-025-01592-y

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