Hydroxytyrosol: A Promising Therapeutic Agent for Mitigating Inflammation and Apoptosis

Inflammation and apoptosis are interrelated biological processes that have a significant impact on the advancement and growth of certain chronic diseases, such as cardiovascular problems, neurological conditions, and osteoarthritis. Recent research has emphasized that focusing on these mechanisms co...

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Main Authors: Wafa Ali Batarfi, Mohd Heikal Mohd Yunus, Adila A. Hamid, Yi Ting Lee, Manira Maarof
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
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Online Access:https://www.mdpi.com/1999-4923/16/12/1504
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Summary:Inflammation and apoptosis are interrelated biological processes that have a significant impact on the advancement and growth of certain chronic diseases, such as cardiovascular problems, neurological conditions, and osteoarthritis. Recent research has emphasized that focusing on these mechanisms could result in novel therapeutic approaches that aim to decrease the severity of diseases and enhance patient outcomes. Hydroxytyrosol (HT), which is well-known for its ability to prevent oxidation, has been identified as a possible candidate for regulating both inflammation and apoptosis. In this review, we will highlight the multifaceted benefits of HT as a therapeutic agent in mitigating inflammation, apoptosis, and associated conditions. This review provides a comprehensive overview of the latest in vitro and in vivo research on the anti-inflammatory and antiapoptotic effects of HT and the mechanisms by which it works. Based on these studies, it is strongly advised to use HT as a bioactive ingredient in pharmaceutical products intended for mitigating inflammation, as well as those with apoptosis applications.
ISSN:1999-4923