Exploring TAS2R46 biomechanics through molecular dynamics and network analysis

Exploring TAS2R46 biomechanics through molecular dynamics and network analysis

Understanding the intricate interplay between structural features and signal-processing events is crucial for unravelling the mechanisms of biomolecular systems. G protein-coupled receptors (GPCRs), a pervasive protein family in humans, serve a wide spectrum of vital functions. TAS2Rs, a subfamily o...

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Bibliographic Details
Main Authors: Marco Cannariato, Riccardo Fanunza, Eric A. Zizzi, Marcello Miceli, Giacomo Di Benedetto, Marco A. Deriu, Lorenzo Pallante
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
bitter taste receptor
TAS2R46
GPCR
strychnine
molecular modelling
network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1473675/full
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