Specific therapeutic options for transthyretin amyloidosis
The epidemiology of systemic amyloidosis has recently undergone a spectacular transformation. While light-chain amyloidosis remains a rare disease with a stable incidence, chronic inflammatory disease associated amyloidosis (AA) is diagnosed less frequently, the incidence of the mutational and wild-...
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| Format: | Article |
| Language: | English |
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Promenade Kft
2024-12-01
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| Series: | Cardiologia Hungarica |
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| Online Access: | https://cardiologia.hungarica.eu/archive/2024-issues/2024-6-contents/specific-therapeutic-options-for-transthyretin-amyloidosis?article=open |
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| _version_ | 1841556790146236416 |
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| author | Zoltán Pozsonyi |
| author_facet | Zoltán Pozsonyi |
| author_sort | Zoltán Pozsonyi |
| collection | DOAJ |
| description | The epidemiology of systemic amyloidosis has recently undergone a spectacular transformation. While light-chain amyloidosis remains a rare disease with a stable incidence, chronic inflammatory disease associated amyloidosis (AA) is diagnosed less frequently, the incidence of the mutational and wild-type forms of ransthyretin amyloidosis (ATTR) has increased dramatically in the developed world. This pectacular increase can be explained by increased diagnostic awareness due to the emergence of new multi-targeted drugs and the spread of simpler, more easily accessible diagnostic methods. In this communication, we summarize the new specific therapeutic options for transthyretin amyloidosis and the new treatment modalities that are expected in the near future. |
| format | Article |
| id | doaj-art-55641b5d364e43b69b1acfac9cefa21f |
| institution | Kabale University |
| issn | 0133-5596 1588-0230 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Promenade Kft |
| record_format | Article |
| series | Cardiologia Hungarica |
| spelling | doaj-art-55641b5d364e43b69b1acfac9cefa21f2025-01-07T06:35:24ZengPromenade KftCardiologia Hungarica0133-55961588-02302024-12-0154649149610.26430/CHUNGARICA.2024.54.6.491Specific therapeutic options for transthyretin amyloidosisZoltán Pozsonyi 0Semmelweis Egyetem, Belgyógyászati és Hematológiai Klinika, BudapestThe epidemiology of systemic amyloidosis has recently undergone a spectacular transformation. While light-chain amyloidosis remains a rare disease with a stable incidence, chronic inflammatory disease associated amyloidosis (AA) is diagnosed less frequently, the incidence of the mutational and wild-type forms of ransthyretin amyloidosis (ATTR) has increased dramatically in the developed world. This pectacular increase can be explained by increased diagnostic awareness due to the emergence of new multi-targeted drugs and the spread of simpler, more easily accessible diagnostic methods. In this communication, we summarize the new specific therapeutic options for transthyretin amyloidosis and the new treatment modalities that are expected in the near future.https://cardiologia.hungarica.eu/archive/2024-issues/2024-6-contents/specific-therapeutic-options-for-transthyretin-amyloidosis?article=opentransthyretin amyloidosisdrug therapyattr cardiomyopathyattr neuropathy |
| spellingShingle | Zoltán Pozsonyi Specific therapeutic options for transthyretin amyloidosis Cardiologia Hungarica transthyretin amyloidosis drug therapy attr cardiomyopathy attr neuropathy |
| title | Specific therapeutic options for transthyretin amyloidosis |
| title_full | Specific therapeutic options for transthyretin amyloidosis |
| title_fullStr | Specific therapeutic options for transthyretin amyloidosis |
| title_full_unstemmed | Specific therapeutic options for transthyretin amyloidosis |
| title_short | Specific therapeutic options for transthyretin amyloidosis |
| title_sort | specific therapeutic options for transthyretin amyloidosis |
| topic | transthyretin amyloidosis drug therapy attr cardiomyopathy attr neuropathy |
| url | https://cardiologia.hungarica.eu/archive/2024-issues/2024-6-contents/specific-therapeutic-options-for-transthyretin-amyloidosis?article=open |
| work_keys_str_mv | AT zoltanpozsonyi specifictherapeuticoptionsfortransthyretinamyloidosis |