Norepinephrine titration in patients with sepsis-induced encephalopathy: cerebral pulsatility index compared to mean arterial pressure guided protocol: randomized controlled trial

Norepinephrine titration in patients with sepsis-induced encephalopathy: cerebral pulsatility index compared to mean arterial pressure guided protocol: randomized controlled trial

Abstract Background Although surviving sepsis campaign (SSC) guidelines are the standard for sepsis and septic shock management, outcomes are still unfavourable. Given that perfusion pressure in sepsis is heterogeneous among patients and within the same patient; we evaluated the impact of individual...

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Bibliographic Details
Main Authors: Mai Salah Salem, Motaz Amr Abosabaa, Mohamed Samir Abd El Ghafar, Hala Mohey EI-Deen Mohamed EI-Gendy, Salah El-din Ibrahim Alsherif
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Anesthesiology
Subjects:
Sepsis-induced encephalopathy
TCD Pulsatility index
Mean arterial pressure
Norepinephrine titration
Cerebral hypoperfusion
ICU mortality
Online Access:https://doi.org/10.1186/s12871-024-02814-0
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