Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million births

Objectives Adverse birth outcomes pose a great threat to the public health and bring a heavy burden of disease in China. A comprehensive examination of the temporal and spatial trends of preterm birth (PTB), low birth weight (LBW) and small for gestational age (SGA) epidemics can provide some elemen...

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Main Authors: Pi Guo, Bing Li, Wu Li, Fei Yao, Ruyin Chen, Jiumin Lin, Qingguo Zhao
Format: Article
Language:English
Published: BMJ Publishing Group 2019-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/11/e030629.full
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author Pi Guo
Bing Li
Wu Li
Fei Yao
Ruyin Chen
Jiumin Lin
Qingguo Zhao
author_facet Pi Guo
Bing Li
Wu Li
Fei Yao
Ruyin Chen
Jiumin Lin
Qingguo Zhao
author_sort Pi Guo
collection DOAJ
description Objectives Adverse birth outcomes pose a great threat to the public health and bring a heavy burden of disease in China. A comprehensive examination of the temporal and spatial trends of preterm birth (PTB), low birth weight (LBW) and small for gestational age (SGA) epidemics can provide some elementary information for subsequent aetiological and epidemiological studies. This study aimed to characterise the spatiotemporal features of PTB, LBW and SGA based on a large cohort of live births in China.Design Spatiotemporal descriptive analysis was performed in Guangdong province, China, from 2014 to 2017.Setting Data involving 2 917 098 live births in Guangdong province, China from 2014 to 2017 was collected from Guangdong Birth Certificate System. Information was collected, including the date of birth, gestational age in week, birth weight, sex of the infant, age of the mother and registered residence of the mother.Results The estimated rate of PTB, LBW and SGA was 4.16%, 4.14% and 12.86%, respectively. For temporal trends, the rates of PTB, LBW and SGA showed seasonal fluctuations, especially for LBW and SGA. In addition, there were regional differences in the rates of PTB, LBW and SGA between the Pearl River Delta and Non-Pearl River Delta regions. From 2014 to 2017, the high rates of PTB and LBW expanded from the Pearl River Delta region to the Non-Pearl River Delta regions. However, compared with the Pearl River Delta region, the rate of SGA was higher in the Non-Pearl River Delta regions on the whole.Conclusion The findings of this study contribute to the understanding of the aetiology and epidemiology of PTB, LBW and SGA in south China.
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spelling doaj-art-55301e58e5f4441a886ec3cdbe6818c02024-11-29T20:50:11ZengBMJ Publishing GroupBMJ Open2044-60552019-11-0191110.1136/bmjopen-2019-030629Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million birthsPi Guo0Bing Li1Wu Li2Fei Yao3Ruyin Chen4Jiumin Lin5Qingguo Zhao62 Department of Preventive Medicine, Shantou University Medical College, Shantou, ChinaDepartment of Economics, Lingnan College, Sun Yat-sen University, Guangzhou, Guangdong, China1 Guangdong Women and Children Hospital, Guangzhou, ChinaShanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China3 Department of Clinical Medicine, Shantou University Medical College, Shantou, China4 Department of Hepatology and Infectious Diseases, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, ChinaEpidemiological Research Office of Key Laboratory of Male Reproduction and Genetics, Family Planning Research Institute of Guangdong Province, Guangzhou, ChinaObjectives Adverse birth outcomes pose a great threat to the public health and bring a heavy burden of disease in China. A comprehensive examination of the temporal and spatial trends of preterm birth (PTB), low birth weight (LBW) and small for gestational age (SGA) epidemics can provide some elementary information for subsequent aetiological and epidemiological studies. This study aimed to characterise the spatiotemporal features of PTB, LBW and SGA based on a large cohort of live births in China.Design Spatiotemporal descriptive analysis was performed in Guangdong province, China, from 2014 to 2017.Setting Data involving 2 917 098 live births in Guangdong province, China from 2014 to 2017 was collected from Guangdong Birth Certificate System. Information was collected, including the date of birth, gestational age in week, birth weight, sex of the infant, age of the mother and registered residence of the mother.Results The estimated rate of PTB, LBW and SGA was 4.16%, 4.14% and 12.86%, respectively. For temporal trends, the rates of PTB, LBW and SGA showed seasonal fluctuations, especially for LBW and SGA. In addition, there were regional differences in the rates of PTB, LBW and SGA between the Pearl River Delta and Non-Pearl River Delta regions. From 2014 to 2017, the high rates of PTB and LBW expanded from the Pearl River Delta region to the Non-Pearl River Delta regions. However, compared with the Pearl River Delta region, the rate of SGA was higher in the Non-Pearl River Delta regions on the whole.Conclusion The findings of this study contribute to the understanding of the aetiology and epidemiology of PTB, LBW and SGA in south China.https://bmjopen.bmj.com/content/9/11/e030629.full
spellingShingle Pi Guo
Bing Li
Wu Li
Fei Yao
Ruyin Chen
Jiumin Lin
Qingguo Zhao
Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million births
BMJ Open
title Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million births
title_full Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million births
title_fullStr Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million births
title_full_unstemmed Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million births
title_short Adverse birth outcomes in Guangdong province, China, 2014–2017: a spatiotemporal analysis of 2.9 million births
title_sort adverse birth outcomes in guangdong province china 2014 2017 a spatiotemporal analysis of 2 9 million births
url https://bmjopen.bmj.com/content/9/11/e030629.full
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