Pathogen reduction diminishes the protective effects of platelets on endothelial barrier permeability in vitro
Abstract: Platelet transfusion not only attenuates bleeding and promotes hemostasis but also plays a critical role in vascular stability and endothelial barrier integrity. Under amotosalen-UVA pathogen reduction of platelets, pathogen nucleic acids undergo adduction, which prevents their replication...
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| Main Authors: | Alison B. Nair, Byron Miyazawa, Alpa Trivedi, Lindsay Vivona, Alexander Fields, Kimberly Herrera, Lucy Z. Kornblith, Joseph Cuschieri, Shibani Pati |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Blood Vessels, Thrombosis & Hemostasis |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950327225000154 |
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