INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITIS

In conditions of experimental acute pancreatitis of 60 guinea pigs and during the treatment of 89 patients with acute pancreatitis it was shown that the use of thioctic acid significantly reduces the manifestations of ischemic symptom , the severity of free radical processes and improves the patient...

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Main Authors: D. B. Demin, M. S. Funyguin, A. A. Chegodaeva, Yu. Yu. Solodov
Format: Article
Language:English
Published: Bashkir State Medical University 2017-01-01
Series:Креативная хирургия и онкология
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Online Access:https://www.surgonco.ru/jour/article/view/30
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author D. B. Demin
M. S. Funyguin
A. A. Chegodaeva
Yu. Yu. Solodov
author_facet D. B. Demin
M. S. Funyguin
A. A. Chegodaeva
Yu. Yu. Solodov
author_sort D. B. Demin
collection DOAJ
description In conditions of experimental acute pancreatitis of 60 guinea pigs and during the treatment of 89 patients with acute pancreatitis it was shown that the use of thioctic acid significantly reduces the manifestations of ischemic symptom , the severity of free radical processes and improves the patient's outcomes. The way for minimally invasive interventions under intraoperative ultrasound navigation consists in layered implementation of minimally invasive access of 2-3 cm in length, followed by the establishment of liquid aspiration from the wound channel of necrotic detritus, while emptying and drainaging the cavity under ultrasound control. The method allows one-step sanitation and drainage of cavity formations containing purulent dense necrotic tissue. This method is efficient, technically feasible in any surgical department, economically rational, since it does not require the purchase of additional surgical equipment. This complex of therapeutic measures allowed to reduce postoperative mortality in case of necrotizing pancreatitis to 9 % during the last three years.
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institution Kabale University
issn 2076-3093
2307-0501
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publishDate 2017-01-01
publisher Bashkir State Medical University
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series Креативная хирургия и онкология
spelling doaj-art-54b57c53fafd4b60a54a58f799e19a6f2025-08-20T03:40:00ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012017-01-0103596210.24060/2076-3093-2014-0-3-59-6230INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITISD. B. Demin0M. S. Funyguin1A. A. Chegodaeva2Yu. Yu. Solodov3Orenburg State Medical AcademyOrenburg State Medical AcademyOrenburg State Medical AcademyOrenburg State Medical AcademyIn conditions of experimental acute pancreatitis of 60 guinea pigs and during the treatment of 89 patients with acute pancreatitis it was shown that the use of thioctic acid significantly reduces the manifestations of ischemic symptom , the severity of free radical processes and improves the patient's outcomes. The way for minimally invasive interventions under intraoperative ultrasound navigation consists in layered implementation of minimally invasive access of 2-3 cm in length, followed by the establishment of liquid aspiration from the wound channel of necrotic detritus, while emptying and drainaging the cavity under ultrasound control. The method allows one-step sanitation and drainage of cavity formations containing purulent dense necrotic tissue. This method is efficient, technically feasible in any surgical department, economically rational, since it does not require the purchase of additional surgical equipment. This complex of therapeutic measures allowed to reduce postoperative mortality in case of necrotizing pancreatitis to 9 % during the last three years.https://www.surgonco.ru/jour/article/view/30acute pancreatitisthioctic acidminimal accessultrasound navigation
spellingShingle D. B. Demin
M. S. Funyguin
A. A. Chegodaeva
Yu. Yu. Solodov
INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITIS
Креативная хирургия и онкология
acute pancreatitis
thioctic acid
minimal access
ultrasound navigation
title INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITIS
title_full INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITIS
title_fullStr INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITIS
title_full_unstemmed INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITIS
title_short INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE PANCREATITIS
title_sort innovative approach to the treatment of acute pancreatitis
topic acute pancreatitis
thioctic acid
minimal access
ultrasound navigation
url https://www.surgonco.ru/jour/article/view/30
work_keys_str_mv AT dbdemin innovativeapproachtothetreatmentofacutepancreatitis
AT msfunyguin innovativeapproachtothetreatmentofacutepancreatitis
AT aachegodaeva innovativeapproachtothetreatmentofacutepancreatitis
AT yuyusolodov innovativeapproachtothetreatmentofacutepancreatitis