Rotating culture regulates the formation of HepaRG-derived liver organoids via YAP translocation
Abstract Background Liver organoid serves as an alternative model for liver pathophysiology in carbohydrate or lipid metabolism and xenobiotic metabolism transformation. Biomechanical cues including spaceflight mission can affect liver organoid construction and their related functions, but their und...
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| Main Authors: | Shaoyu Zhong, Lu Zheng, Yi Wu, Shujin Sun, Qing Luo, Guanbin Song, Dongyuan Lü, Mian Long |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
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| Series: | BMC Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12915-024-02062-1 |
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