Single prolonged stress induces behavior and transcriptomic changes in the medial prefrontal cortex to increase susceptibility to anxiety-like behavior in rats

Single prolonged stress induces behavior and transcriptomic changes in the medial prefrontal cortex to increase susceptibility to anxiety-like behavior in rats

IntroductionTranscriptomic studies offer valuable insights into the pathophysiology of traumatic stress-induced neuropsychiatric disorders, including generalized anxiety disorder and post-traumatic stress disorder (PTSD). The medial prefrontal cortex (mPFC) has been implicated in emotion, cognitive...

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Bibliographic Details
Main Authors:	Javed Iqbal, Geng-Di Huang, Dan Shen, Yan-Xue Xue, Mei Yang, Xiao-Jian Jia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Series:	Frontiers in Psychiatry
Subjects:	traumatic stress prefrontal cortex susceptibility resilient anxiety
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1472194/full
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