Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MS

A method, improved d-SPE extration couple with ultra performance liquid chromatography tandem-mass spectrometry (UPLC-MS/MS), was developed for the determination of pentachlorophenol and its sodium salt residue in eggs. The sodium pentachlorophenol in the eggs was converted firstly into pentachlorop...

Full description

Saved in:
Bibliographic Details
Main Authors: Nengming Chu, Manli Xie, Xia Meng, Xiaobing Qin, Shufang Jiang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:CyTA - Journal of Food
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2024.2377308
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846116810717396992
author Nengming Chu
Manli Xie
Xia Meng
Xiaobing Qin
Shufang Jiang
author_facet Nengming Chu
Manli Xie
Xia Meng
Xiaobing Qin
Shufang Jiang
author_sort Nengming Chu
collection DOAJ
description A method, improved d-SPE extration couple with ultra performance liquid chromatography tandem-mass spectrometry (UPLC-MS/MS), was developed for the determination of pentachlorophenol and its sodium salt residue in eggs. The sodium pentachlorophenol in the eggs was converted firstly into pentachlorophenol under acidic conditions, extracted by 1.5% (v/v) acetic acid/acetonitril, and the extraction solution was purified finally by disperse solid phase extraction. The composition of dispersive sorbents was optimized based on the recoveries and matrix effects. The recoveries at fortification levels of 0.5, 5 and 50.0 μg/kg in eggs ranged from 72.2% to 89.8% with the relative standard deviations of 0.2%~0.8%. The limits of quantification (LOQ) was 0.5 μg/kg. Market samples were quantified, and PCP residues were found, but all the detection levels were below the method LOQ. We demonstrated that UPLC – MS/MS in combination with modified d-SPE can be used to routinely monitor PCP residues in egg samples.
format Article
id doaj-art-53cf4b8e5afc41b58ef92a1b4274c11c
institution Kabale University
issn 1947-6337
1947-6345
language English
publishDate 2024-12-01
publisher Taylor & Francis Group
record_format Article
series CyTA - Journal of Food
spelling doaj-art-53cf4b8e5afc41b58ef92a1b4274c11c2024-12-18T13:34:52ZengTaylor & Francis GroupCyTA - Journal of Food1947-63371947-63452024-12-0122110.1080/19476337.2024.2377308Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MSNengming Chu0Manli Xie1Xia Meng2Xiaobing Qin3Shufang Jiang4Chongqing Academy of Agricultural Science, Chongqing, P.R. ChinaChongqing Academy of Agricultural Science, Chongqing, P.R. ChinaChongqing Academy of Agricultural Science, Chongqing, P.R. ChinaBeibei Agriculture and Rural Committee, Chongqing, P.R. ChinaKaizhou Agricultural Development Service Center, Chongqing, P.R. ChinaA method, improved d-SPE extration couple with ultra performance liquid chromatography tandem-mass spectrometry (UPLC-MS/MS), was developed for the determination of pentachlorophenol and its sodium salt residue in eggs. The sodium pentachlorophenol in the eggs was converted firstly into pentachlorophenol under acidic conditions, extracted by 1.5% (v/v) acetic acid/acetonitril, and the extraction solution was purified finally by disperse solid phase extraction. The composition of dispersive sorbents was optimized based on the recoveries and matrix effects. The recoveries at fortification levels of 0.5, 5 and 50.0 μg/kg in eggs ranged from 72.2% to 89.8% with the relative standard deviations of 0.2%~0.8%. The limits of quantification (LOQ) was 0.5 μg/kg. Market samples were quantified, and PCP residues were found, but all the detection levels were below the method LOQ. We demonstrated that UPLC – MS/MS in combination with modified d-SPE can be used to routinely monitor PCP residues in egg samples.https://www.tandfonline.com/doi/10.1080/19476337.2024.2377308PCP&Na-PCPd-SPEQuEChERSeggsUPLC-MS/MS
spellingShingle Nengming Chu
Manli Xie
Xia Meng
Xiaobing Qin
Shufang Jiang
Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MS
CyTA - Journal of Food
PCP&Na-PCP
d-SPE
QuEChERS
eggs
UPLC-MS/MS
title Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MS
title_full Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MS
title_fullStr Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MS
title_full_unstemmed Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MS
title_short Determination of pentachlorophenol and its sodium salt residue in eggs using d-SPE method coupled with UPLC-MS/MS
title_sort determination of pentachlorophenol and its sodium salt residue in eggs using d spe method coupled with uplc ms ms
topic PCP&Na-PCP
d-SPE
QuEChERS
eggs
UPLC-MS/MS
url https://www.tandfonline.com/doi/10.1080/19476337.2024.2377308
work_keys_str_mv AT nengmingchu determinationofpentachlorophenolanditssodiumsaltresidueineggsusingdspemethodcoupledwithuplcmsms
AT manlixie determinationofpentachlorophenolanditssodiumsaltresidueineggsusingdspemethodcoupledwithuplcmsms
AT xiameng determinationofpentachlorophenolanditssodiumsaltresidueineggsusingdspemethodcoupledwithuplcmsms
AT xiaobingqin determinationofpentachlorophenolanditssodiumsaltresidueineggsusingdspemethodcoupledwithuplcmsms
AT shufangjiang determinationofpentachlorophenolanditssodiumsaltresidueineggsusingdspemethodcoupledwithuplcmsms