Enhancing Antileishmanial Activity of Amidoxime-Based Compounds Bearing a 4,5-Dihydrofuran Scaffold: In Vitro Screening Against <i>Leishmania amazonensis</i>

Enhancing Antileishmanial Activity of Amidoxime-Based Compounds Bearing a 4,5-Dihydrofuran Scaffold: In Vitro Screening Against <i>Leishmania amazonensis</i>

Leishmaniasis, a protozoan disease affecting humans, exposes significant shortcomings in current treatments. In continuation to our previous findings on amidoxime-based antileishmanial compounds bearing a 4,5-dihydrofuran scaffold, twelve new amidoxime derivatives substituted at position 3 with an a...

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Bibliographic Details
Main Authors: Fabiana Maia Santos Urbancg Moncorvo, Oscar Leonardo Avendaño Leon, Christophe Curti, Youssef Kabri, Sébastien Redon, Eduardo Caio Torres-Santos, Patrice Vanelle
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
leishmaniasis
pharmacomodulation
4,5-dihydrofuran
amidoxime
manganese (III) acetate
Online Access:https://www.mdpi.com/1420-3049/29/22/5469
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