Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image

Peripheral Nerve Sheath (PNS) tumours are rare neoplasms arising from deeper soft tissues, peripheral nerves, perineural cells, or Schwann cells with ectomesenchymal origins [1]. The incidence rate is between 4-13%, with the upper extremity being the most commonly involved site (45%) [2]. The role o...

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Main Authors: Shreya Giri Goswami, Poornima Pandey, Jayashree Bhawani
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2025-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/20434/75618_CE[Ra1]_F(IS)_QC(AN_IS)_PF1(AG_OM)_PFA_NC(IS)_PN(IS).pdf
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author Shreya Giri Goswami
Poornima Pandey
Jayashree Bhawani
author_facet Shreya Giri Goswami
Poornima Pandey
Jayashree Bhawani
author_sort Shreya Giri Goswami
collection DOAJ
description Peripheral Nerve Sheath (PNS) tumours are rare neoplasms arising from deeper soft tissues, peripheral nerves, perineural cells, or Schwann cells with ectomesenchymal origins [1]. The incidence rate is between 4-13%, with the upper extremity being the most commonly involved site (45%) [2]. The role of Fine Needle Aspiration Cytology (FNAC), based on the cytomorphology of these neoplasms of the PNS, is challenging and often confusing, underscoring the complex diagnostic nature of the lesions. Therefore, FNAC details were highlighted by presenting a clinicopathological image and providing insight into the intricate cytomorphology involved.
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institution Kabale University
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publisher JCDR Research and Publications Private Limited
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series Journal of Clinical and Diagnostic Research
spelling doaj-art-53a2fe0f20cf4b25a54913e34a925a2c2025-01-08T12:13:38ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-01-011901010310.7860/JCDR/2025/75618.20434Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological ImageShreya Giri Goswami0Poornima Pandey1Jayashree Bhawani2Junior Resident, Department of Pathology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Senior Resident, Department of Pathology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Junior Resident, Department of Pathology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.Peripheral Nerve Sheath (PNS) tumours are rare neoplasms arising from deeper soft tissues, peripheral nerves, perineural cells, or Schwann cells with ectomesenchymal origins [1]. The incidence rate is between 4-13%, with the upper extremity being the most commonly involved site (45%) [2]. The role of Fine Needle Aspiration Cytology (FNAC), based on the cytomorphology of these neoplasms of the PNS, is challenging and often confusing, underscoring the complex diagnostic nature of the lesions. Therefore, FNAC details were highlighted by presenting a clinicopathological image and providing insight into the intricate cytomorphology involved.https://www.jcdr.net/articles/PDF/20434/75618_CE[Ra1]_F(IS)_QC(AN_IS)_PF1(AG_OM)_PFA_NC(IS)_PN(IS).pdfcytomorphologyfine needle aspiration cytologyforearm swellingmalignant mesenchymal tumourperipheral nerve sheath tumoursoft-tissue tumour
spellingShingle Shreya Giri Goswami
Poornima Pandey
Jayashree Bhawani
Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image
Journal of Clinical and Diagnostic Research
cytomorphology
fine needle aspiration cytology
forearm swelling
malignant mesenchymal tumour
peripheral nerve sheath tumour
soft-tissue tumour
title Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image
title_full Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image
title_fullStr Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image
title_full_unstemmed Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image
title_short Unveiling the Cytological Enigma of Malignant Spindle Cell Neoplasm of Peripheral Nerve Sheath: A Clinicopathological Image
title_sort unveiling the cytological enigma of malignant spindle cell neoplasm of peripheral nerve sheath a clinicopathological image
topic cytomorphology
fine needle aspiration cytology
forearm swelling
malignant mesenchymal tumour
peripheral nerve sheath tumour
soft-tissue tumour
url https://www.jcdr.net/articles/PDF/20434/75618_CE[Ra1]_F(IS)_QC(AN_IS)_PF1(AG_OM)_PFA_NC(IS)_PN(IS).pdf
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AT jayashreebhawani unveilingthecytologicalenigmaofmalignantspindlecellneoplasmofperipheralnervesheathaclinicopathologicalimage