Assessment of DRB1 and DQB1 genotype frequencies in type 1 diabetes: a gender-based study in Sudanese children

Assessment of DRB1 and DQB1 genotype frequencies in type 1 diabetes: a gender-based study in Sudanese children

Background & Aims: Type 1 diabetes mellitus (T1DM) is an autoimmune condition characterized by the destruction of pancreatic β-cells. While environmental factors and autoantibodies play a role, genetic predisposition, particularly involving HLA class II alleles (DR and DQ), is significant. This...

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Bibliographic Details
Main Authors: Hiba Omer AbdelRhman Hussein, Sababil Salih Abdalla, Sakeena NourEldine Salih, Abdelkarim A. Abdrabo, Mohamed Abdelgadir Mahdi
Format: Article
Language:English
Published: Urmia University of Medical Sciences 2024-11-01
Series:Journal of Research in Applied and Basic Medical Sciences
Subjects:
drb1 and dqb1 alleles
gender differences
genetic predisposition
hla genotypes
type 1 diabetes mellitus (t1dm)
Online Access:http://ijrabms.umsu.ac.ir/article-1-363-en.pdf
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