Quercetin Attenuates Oxidative Stress and Apoptosis in Brain Tissue of APP/PS1 Double Transgenic AD Mice by Regulating Keap1/Nrf2/HO-1 Pathway to Improve Cognitive Impairment

Quercetin Attenuates Oxidative Stress and Apoptosis in Brain Tissue of APP/PS1 Double Transgenic AD Mice by Regulating Keap1/Nrf2/HO-1 Pathway to Improve Cognitive Impairment

Conclusion: Quercetin can improve cognitive impairment and AD-like pathology in APP/PS1 double transgenic mice, potentially related to quercetin’s activation of the Keap1/Nrf2/HO-1 pathway and reduction of cell apoptosis.

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Bibliographic Details
Main Authors: Meijia Cheng, Changbin Yuan, Yetao Ju, Yongming Liu, Baorui Shi, Yali Yang, Sian Jin, Xiaoming He, Li Zhang, Dongyu Min
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2024/5698119
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