On the origin of mitosis-derived human embryo aneuploidy
Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell imaging, three recent studies identify spindle architecture and positioning features that could provide insights into why early embry...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-54953-0 |
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| _version_ | 1846147579329380352 |
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| author | Jiyeon Leem Madison Gowett Sarah Bolarinwa Binyam Mogessie |
| author_facet | Jiyeon Leem Madison Gowett Sarah Bolarinwa Binyam Mogessie |
| author_sort | Jiyeon Leem |
| collection | DOAJ |
| description | Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell imaging, three recent studies identify spindle architecture and positioning features that could provide insights into why early embryos are predisposed to chromosomal abnormalities. |
| format | Article |
| id | doaj-art-5325f22a76134d09992a723d2ca127cc |
| institution | Kabale University |
| issn | 2041-1723 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-5325f22a76134d09992a723d2ca127cc2024-12-01T12:36:23ZengNature PortfolioNature Communications2041-17232024-11-011511310.1038/s41467-024-54953-0On the origin of mitosis-derived human embryo aneuploidyJiyeon Leem0Madison Gowett1Sarah Bolarinwa2Binyam Mogessie3Department of Molecular, Cellular, and Developmental Biology, Yale UniversityDepartment of Molecular, Cellular, and Developmental Biology, Yale UniversityDepartment of Molecular, Cellular, and Developmental Biology, Yale UniversityDepartment of Molecular, Cellular, and Developmental Biology, Yale UniversityChromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell imaging, three recent studies identify spindle architecture and positioning features that could provide insights into why early embryos are predisposed to chromosomal abnormalities.https://doi.org/10.1038/s41467-024-54953-0 |
| spellingShingle | Jiyeon Leem Madison Gowett Sarah Bolarinwa Binyam Mogessie On the origin of mitosis-derived human embryo aneuploidy Nature Communications |
| title | On the origin of mitosis-derived human embryo aneuploidy |
| title_full | On the origin of mitosis-derived human embryo aneuploidy |
| title_fullStr | On the origin of mitosis-derived human embryo aneuploidy |
| title_full_unstemmed | On the origin of mitosis-derived human embryo aneuploidy |
| title_short | On the origin of mitosis-derived human embryo aneuploidy |
| title_sort | on the origin of mitosis derived human embryo aneuploidy |
| url | https://doi.org/10.1038/s41467-024-54953-0 |
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