Switchable ROS generator and scavenger to prevent the cisplatin induced acute kidney injury and improve efficacy via synergistic chemodynamic/immune therapy

Switchable ROS generator and scavenger to prevent the cisplatin induced acute kidney injury and improve efficacy via synergistic chemodynamic/immune therapy

Acute kidney injury (AKI) induced by cisplatin (DDP), which is accompanied with the generation of reactive oxygen species (ROS), is a severe side effect during treatment and restricts the application of DDP. In this study, we develop ultrasmall Mn3O4 nanozyme (UMON) with tumor microenvironment (TME)...

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Bibliographic Details
Main Authors: Yanan Ren, Fei Wu, Linlin Huo, Xiao Wang, Yong Zhang, Mengke Fan, Mingya Tan, Jiayi Zhao, Jingliang Cheng, Zhenghuan Zhao, Jianfeng Bao
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Switchable ROS scavenger/generator
Cisplatin adjuvant
Acute kidney injury
Improved therapeutic efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424003892
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