Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis
Drug-eluting stents (DES) are the gold standard for percutaneous coronary interventions (PCI); however, technical and anatomical challenges need to be addressed to ensure optimal apposition and prevent late adverse events. Complex vessel anatomies, including ectatic or aneurysmatic vessels, or signi...
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Radcliffe Medical Media
2020-09-01
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| Series: | US Cardiology Review |
| Online Access: | https://www.uscjournal.com/articles/feasibility-safety-and-clinical-performance |
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| author | Krzysztof Pujdak Jan Kähler Marc Werner |
| author_facet | Krzysztof Pujdak Jan Kähler Marc Werner |
| author_sort | Krzysztof Pujdak |
| collection | DOAJ |
| description | Drug-eluting stents (DES) are the gold standard for percutaneous coronary interventions (PCI); however, technical and anatomical challenges need to be addressed to ensure optimal apposition and prevent late adverse events. Complex vessel anatomies, including ectatic or aneurysmatic vessels, or significant differences in diameter in left main stenosis of the coronary artery, are clinical indications in which current PCI techniques attempt to shape conventional DES to follow vessel anatomy, thus modifying the original stent scaffold and its properties. However, due to their design, balloon-expandable cobalt–chromium and cobalt–nickel DES have limitations regarding their expansion capacity, which can result in undersizing and malapposition. New stent scaffolds have recently been introduced into clinical practice to address these challenging anatomies, including a drug-eluting nitinol stent platform. The nature of the nitinol device allows conformability to the native vessel, covering complex anatomies without manual adaptation. In this article, the authors present the rationale and current data on self-apposing nitinol DES in left main stenosis, and suggest that the device may be safely and effectively used with comparable rates of adverse cardiovascular events, as seen with second-generation balloon-expandable DES. |
| format | Article |
| id | doaj-art-5318c5ae0cd64891a9d6af3d45d0b970 |
| institution | Kabale University |
| issn | 1758-3896 1758-390X |
| language | English |
| publishDate | 2020-09-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | US Cardiology Review |
| spelling | doaj-art-5318c5ae0cd64891a9d6af3d45d0b9702024-12-14T16:02:22ZengRadcliffe Medical MediaUS Cardiology Review1758-38961758-390X2020-09-011410.15420/usc.2020.11Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main StenosisKrzysztof Pujdak0Jan Kähler1Marc Werner2Department of Cardiology, Klinikum Herford, Herford, GermanyDepartment of Cardiology, Klinikum Herford, Herford, GermanyDepartment of Cardiology, Klinikum Herford, Herford, GermanyDrug-eluting stents (DES) are the gold standard for percutaneous coronary interventions (PCI); however, technical and anatomical challenges need to be addressed to ensure optimal apposition and prevent late adverse events. Complex vessel anatomies, including ectatic or aneurysmatic vessels, or significant differences in diameter in left main stenosis of the coronary artery, are clinical indications in which current PCI techniques attempt to shape conventional DES to follow vessel anatomy, thus modifying the original stent scaffold and its properties. However, due to their design, balloon-expandable cobalt–chromium and cobalt–nickel DES have limitations regarding their expansion capacity, which can result in undersizing and malapposition. New stent scaffolds have recently been introduced into clinical practice to address these challenging anatomies, including a drug-eluting nitinol stent platform. The nature of the nitinol device allows conformability to the native vessel, covering complex anatomies without manual adaptation. In this article, the authors present the rationale and current data on self-apposing nitinol DES in left main stenosis, and suggest that the device may be safely and effectively used with comparable rates of adverse cardiovascular events, as seen with second-generation balloon-expandable DES.https://www.uscjournal.com/articles/feasibility-safety-and-clinical-performance |
| spellingShingle | Krzysztof Pujdak Jan Kähler Marc Werner Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis US Cardiology Review |
| title | Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis |
| title_full | Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis |
| title_fullStr | Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis |
| title_full_unstemmed | Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis |
| title_short | Feasibility, Safety, and Clinical Performance of Self-apposing Stents for Left Main Stenosis |
| title_sort | feasibility safety and clinical performance of self apposing stents for left main stenosis |
| url | https://www.uscjournal.com/articles/feasibility-safety-and-clinical-performance |
| work_keys_str_mv | AT krzysztofpujdak feasibilitysafetyandclinicalperformanceofselfapposingstentsforleftmainstenosis AT jankahler feasibilitysafetyandclinicalperformanceofselfapposingstentsforleftmainstenosis AT marcwerner feasibilitysafetyandclinicalperformanceofselfapposingstentsforleftmainstenosis |