Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment
Objectives: This study aimed to establish standard transesophageal echocardiographic (TEE) measurements of left ventricular (LV) morphology, function, and myocardial work parameters in healthy Beagle dogs using pressure-strain loops (PSL). Additionally, it sought to standardize optimal TEE imaging t...
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Elsevier
2025-01-01
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024171228 |
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| author | Beibei Ge Changqing Miao Di Xu Mingxia Li Fang Xu Xiaoxian Wang Fen Chen Yan Li Yan Chen Chanjuan Gong Peng Li Fang Wang Jing Yao |
| author_facet | Beibei Ge Changqing Miao Di Xu Mingxia Li Fang Xu Xiaoxian Wang Fen Chen Yan Li Yan Chen Chanjuan Gong Peng Li Fang Wang Jing Yao |
| author_sort | Beibei Ge |
| collection | DOAJ |
| description | Objectives: This study aimed to establish standard transesophageal echocardiographic (TEE) measurements of left ventricular (LV) morphology, function, and myocardial work parameters in healthy Beagle dogs using pressure-strain loops (PSL). Additionally, it sought to standardize optimal TEE imaging techniques and explore the potiential application of myocardial work analyis in veterinary medicine. Methods: Thirty-seven healthy male Beagle dogs were anesthetized, intubated, and mechanically ventilated for TEE examinations. LV systolic and diastolic function were evaluated, with simultaneous invasive femoral artery pressure measurements. Left ventricular global longitudinal strain (GLS), myocardial work parameters, PSL-derived metrics were analyzed. Results: The mean LV GLS was −16.0 ± 4.0 %, and the LV global myocardial work index (GWI) was 888 ± 298.6 mmHg∗%. Global Myocardial work efficiency (GWE) was 88 ± 3 %, while global myocardial wasted work (GWW) was 152 mmHg∗% (38–431 mmHg∗%). LV ejection fraction (LVEF) averaged 58.7 ± 4.4 %. Left ventricular end-diastolic (LVEDV) and end-systolic volume (LVESV) were 19.3 ± 5.2 ml and 8.0 ± 2.3 ml, respectively. Regional myocardial work analysis revealed significant differences between the interventricular septum and lateral wall. The lateral wall demonstrated reduced segmental work efficiency (SWE), work index (SWI), and constructive work (SCW) but higher wasted work (SWW) compared to the septum (p < 0.05). Conclusions: TEE provides detail morphological and functional assessments of the Beagle hearts, offering reference data for future studies. Myocardial work analysis presents a novel method for evaluate myocardial contractility and mechanical properties, with promising applicatons in veterinary medicine. |
| format | Article |
| id | doaj-art-52f6da9de42f496d875deed7f63b5b10 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-52f6da9de42f496d875deed7f63b5b102025-01-17T04:50:07ZengElsevierHeliyon2405-84402025-01-01111e41091Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessmentBeibei Ge0Changqing Miao1Di Xu2Mingxia Li3Fang Xu4Xiaoxian Wang5Fen Chen6Yan Li7Yan Chen8Chanjuan Gong9Peng Li10Fang Wang11Jing Yao12Department of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of ChinaDepartment of Cardiology, Jiangyin People’s Hospital, Jiangyin, 214499, People's Republic of ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of ChinaDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of ChinaDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of ChinaDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of ChinaDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of ChinaDepartment of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of ChinaDepartment of Cardiology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210018, People's Republic of ChinaDepartment of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of ChinaDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of ChinaDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China; Medical Imaging Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, People's Republic of China; Corresponding author. 321 Zhongshan Road, Nanjing, 210008, People's Republic of China.Objectives: This study aimed to establish standard transesophageal echocardiographic (TEE) measurements of left ventricular (LV) morphology, function, and myocardial work parameters in healthy Beagle dogs using pressure-strain loops (PSL). Additionally, it sought to standardize optimal TEE imaging techniques and explore the potiential application of myocardial work analyis in veterinary medicine. Methods: Thirty-seven healthy male Beagle dogs were anesthetized, intubated, and mechanically ventilated for TEE examinations. LV systolic and diastolic function were evaluated, with simultaneous invasive femoral artery pressure measurements. Left ventricular global longitudinal strain (GLS), myocardial work parameters, PSL-derived metrics were analyzed. Results: The mean LV GLS was −16.0 ± 4.0 %, and the LV global myocardial work index (GWI) was 888 ± 298.6 mmHg∗%. Global Myocardial work efficiency (GWE) was 88 ± 3 %, while global myocardial wasted work (GWW) was 152 mmHg∗% (38–431 mmHg∗%). LV ejection fraction (LVEF) averaged 58.7 ± 4.4 %. Left ventricular end-diastolic (LVEDV) and end-systolic volume (LVESV) were 19.3 ± 5.2 ml and 8.0 ± 2.3 ml, respectively. Regional myocardial work analysis revealed significant differences between the interventricular septum and lateral wall. The lateral wall demonstrated reduced segmental work efficiency (SWE), work index (SWI), and constructive work (SCW) but higher wasted work (SWW) compared to the septum (p < 0.05). Conclusions: TEE provides detail morphological and functional assessments of the Beagle hearts, offering reference data for future studies. Myocardial work analysis presents a novel method for evaluate myocardial contractility and mechanical properties, with promising applicatons in veterinary medicine.http://www.sciencedirect.com/science/article/pii/S2405844024171228Transesophageal echocardiographyBeagle dogMyocardial workSpeckle tracking echocardiography |
| spellingShingle | Beibei Ge Changqing Miao Di Xu Mingxia Li Fang Xu Xiaoxian Wang Fen Chen Yan Li Yan Chen Chanjuan Gong Peng Li Fang Wang Jing Yao Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment Heliyon Transesophageal echocardiography Beagle dog Myocardial work Speckle tracking echocardiography |
| title | Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment |
| title_full | Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment |
| title_fullStr | Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment |
| title_full_unstemmed | Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment |
| title_short | Evaluating cardiac performance in beagle dogs: Transesophageal echocardiography and myocardial work assessment |
| title_sort | evaluating cardiac performance in beagle dogs transesophageal echocardiography and myocardial work assessment |
| topic | Transesophageal echocardiography Beagle dog Myocardial work Speckle tracking echocardiography |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024171228 |
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