Sericin coats of silk fibres, a degumming waste or future material?
Silk is a fibrous biopolymer with a recorded history in the textile industries for centuries. This fibre is constituted of two different proteins: fibroin and sericin, of which the latter accounting for approximately 20–30 % of the silk mass. Silk sericin (SSER) was previously considered as a waste...
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| Language: | English |
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Elsevier
2024-12-01
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| Series: | Materials Today Bio |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590006424003673 |
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| author | Yunong Yuan Mohammad Nasri Azadeh Manayi Junying Zhang Chunyong Wu Tae-Joon Jeon Lifeng Kang |
| author_facet | Yunong Yuan Mohammad Nasri Azadeh Manayi Junying Zhang Chunyong Wu Tae-Joon Jeon Lifeng Kang |
| author_sort | Yunong Yuan |
| collection | DOAJ |
| description | Silk is a fibrous biopolymer with a recorded history in the textile industries for centuries. This fibre is constituted of two different proteins: fibroin and sericin, of which the latter accounting for approximately 20–30 % of the silk mass. Silk sericin (SSER) was previously considered as a waste by-product in silk fibroin extraction. SSER has recently garnered significant scientific interest due to its extensive biological and pharmacological properties. These include antioxidant effects, biocompatibility, low immunogenicity, controlled biodegradability, and the ability to induce cell proliferation. This review covers studies about various aspects of this emerging material, namely, its general morphology, specific structure, molecular weight, features of different layers, and gene sequences. The impact of different extraction methods and the application of extracted SSER based on molecular weight are discussed. Additionally, the characteristic functional groups in the amino acids of sericin facilitate its applications in regenerative medicine, wound healing, drug delivery, textile, environment, and energy, in various forms like hydrogels, films, scaffolds, and conduits. SSER-based materials offer great potentials for multi-functional applications in the upcoming decades, showcasing adaptability for various functional uses and promising future technological advancements. |
| format | Article |
| id | doaj-art-52e9db460000435f8190a9398c81ca3c |
| institution | Kabale University |
| issn | 2590-0064 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials Today Bio |
| spelling | doaj-art-52e9db460000435f8190a9398c81ca3c2024-12-14T06:32:13ZengElsevierMaterials Today Bio2590-00642024-12-0129101306Sericin coats of silk fibres, a degumming waste or future material?Yunong Yuan0Mohammad Nasri1Azadeh Manayi2Junying Zhang3Chunyong Wu4Tae-Joon Jeon5Lifeng Kang6School of Pharmacy, Faculty of Medicine and Health, University of Sydney, Pharmacy and Bank Building A15, Science Road, New South Wales 2006, Australia; Sydney Nano Institute, University of Sydney, NSW, 2006, AustraliaSchool of Pharmacy, Faculty of Medicine and Health, University of Sydney, Pharmacy and Bank Building A15, Science Road, New South Wales 2006, AustraliaSchool of Pharmacy, Faculty of Medicine and Health, University of Sydney, Pharmacy and Bank Building A15, Science Road, New South Wales 2006, Australia; Medicinal Plants Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, IranDepartment of TCMs Pharmaceuticals, China Pharmaceutical University, Nanjing, 210009, ChinaDepartment of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, 210009, ChinaDepartment of Biological Sciences and Bioengineering, Inha University, 100 Inha-ro, Michuhol-gu, Incheon, 22212, Republic of KoreaSchool of Pharmacy, Faculty of Medicine and Health, University of Sydney, Pharmacy and Bank Building A15, Science Road, New South Wales 2006, Australia; Sydney Nano Institute, University of Sydney, NSW, 2006, Australia; Corresponding author. School of Pharmacy, Faculty of Medicine and Health, University of Sydney, Pharmacy and Bank Building A15, Science Road, New South Wales 2006, Australia.Silk is a fibrous biopolymer with a recorded history in the textile industries for centuries. This fibre is constituted of two different proteins: fibroin and sericin, of which the latter accounting for approximately 20–30 % of the silk mass. Silk sericin (SSER) was previously considered as a waste by-product in silk fibroin extraction. SSER has recently garnered significant scientific interest due to its extensive biological and pharmacological properties. These include antioxidant effects, biocompatibility, low immunogenicity, controlled biodegradability, and the ability to induce cell proliferation. This review covers studies about various aspects of this emerging material, namely, its general morphology, specific structure, molecular weight, features of different layers, and gene sequences. The impact of different extraction methods and the application of extracted SSER based on molecular weight are discussed. Additionally, the characteristic functional groups in the amino acids of sericin facilitate its applications in regenerative medicine, wound healing, drug delivery, textile, environment, and energy, in various forms like hydrogels, films, scaffolds, and conduits. SSER-based materials offer great potentials for multi-functional applications in the upcoming decades, showcasing adaptability for various functional uses and promising future technological advancements.http://www.sciencedirect.com/science/article/pii/S2590006424003673Silk sericinBiomaterialsDrug deliveryRegenerationEnergyPro-environment |
| spellingShingle | Yunong Yuan Mohammad Nasri Azadeh Manayi Junying Zhang Chunyong Wu Tae-Joon Jeon Lifeng Kang Sericin coats of silk fibres, a degumming waste or future material? Materials Today Bio Silk sericin Biomaterials Drug delivery Regeneration Energy Pro-environment |
| title | Sericin coats of silk fibres, a degumming waste or future material? |
| title_full | Sericin coats of silk fibres, a degumming waste or future material? |
| title_fullStr | Sericin coats of silk fibres, a degumming waste or future material? |
| title_full_unstemmed | Sericin coats of silk fibres, a degumming waste or future material? |
| title_short | Sericin coats of silk fibres, a degumming waste or future material? |
| title_sort | sericin coats of silk fibres a degumming waste or future material |
| topic | Silk sericin Biomaterials Drug delivery Regeneration Energy Pro-environment |
| url | http://www.sciencedirect.com/science/article/pii/S2590006424003673 |
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