Olanzapine-induced Pancytopenia: Case Report
In the field of antipsychotic medicines, clozapine and olanzapine are both structurally and functionally similar. This case study describes a 35-year-old man with paranoid schizophrenia who experienced a rare case of olanzapine-induced pancytopenia. The patient required blood transfusions due to sev...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Medical Journal of Dr. D.Y. Patil Vidyapeeth |
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| Online Access: | https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_13_24 |
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| author | A Prajnashree S. K Someshwar Arfa A Sayed K P Abhirami Sanatkumar B. Nyamagoud |
| author_facet | A Prajnashree S. K Someshwar Arfa A Sayed K P Abhirami Sanatkumar B. Nyamagoud |
| author_sort | A Prajnashree |
| collection | DOAJ |
| description | In the field of antipsychotic medicines, clozapine and olanzapine are both structurally and functionally similar. This case study describes a 35-year-old man with paranoid schizophrenia who experienced a rare case of olanzapine-induced pancytopenia. The patient required blood transfusions due to severe pancytopenia while receiving olanzapine treatment. The study emphasizes how crucial it is to acknowledge pancytopenia caused by olanzapine as a rare but significant medication-induced risk. It is recommended that clinicians exercise caution, perform routine hematologic assessments, and participate in ongoing investigations into this rare adverse event. However, sporadic reports of olanzapine-induced pancytopenia in schizophrenia patients have surfaced. This hematologic effect’s precise mechanism is still unknown. |
| format | Article |
| id | doaj-art-52bd86ceb0a1476b8ac1ceb5771a4475 |
| institution | Kabale University |
| issn | 2589-8302 2589-8310 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Dr. D.Y. Patil Vidyapeeth |
| spelling | doaj-art-52bd86ceb0a1476b8ac1ceb5771a44752024-12-12T07:35:53ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil Vidyapeeth2589-83022589-83102024-11-0117Suppl 2S377S37910.4103/mjdrdypu.mjdrdypu_13_24Olanzapine-induced Pancytopenia: Case ReportA PrajnashreeS. K SomeshwarArfa A SayedK P AbhiramiSanatkumar B. NyamagoudIn the field of antipsychotic medicines, clozapine and olanzapine are both structurally and functionally similar. This case study describes a 35-year-old man with paranoid schizophrenia who experienced a rare case of olanzapine-induced pancytopenia. The patient required blood transfusions due to severe pancytopenia while receiving olanzapine treatment. The study emphasizes how crucial it is to acknowledge pancytopenia caused by olanzapine as a rare but significant medication-induced risk. It is recommended that clinicians exercise caution, perform routine hematologic assessments, and participate in ongoing investigations into this rare adverse event. However, sporadic reports of olanzapine-induced pancytopenia in schizophrenia patients have surfaced. This hematologic effect’s precise mechanism is still unknown.https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_13_24antipsychoticclozapineolanzapinepancytopeniaschizophrenia |
| spellingShingle | A Prajnashree S. K Someshwar Arfa A Sayed K P Abhirami Sanatkumar B. Nyamagoud Olanzapine-induced Pancytopenia: Case Report Medical Journal of Dr. D.Y. Patil Vidyapeeth antipsychotic clozapine olanzapine pancytopenia schizophrenia |
| title | Olanzapine-induced Pancytopenia: Case Report |
| title_full | Olanzapine-induced Pancytopenia: Case Report |
| title_fullStr | Olanzapine-induced Pancytopenia: Case Report |
| title_full_unstemmed | Olanzapine-induced Pancytopenia: Case Report |
| title_short | Olanzapine-induced Pancytopenia: Case Report |
| title_sort | olanzapine induced pancytopenia case report |
| topic | antipsychotic clozapine olanzapine pancytopenia schizophrenia |
| url | https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_13_24 |
| work_keys_str_mv | AT aprajnashree olanzapineinducedpancytopeniacasereport AT sksomeshwar olanzapineinducedpancytopeniacasereport AT arfaasayed olanzapineinducedpancytopeniacasereport AT kpabhirami olanzapineinducedpancytopeniacasereport AT sanatkumarbnyamagoud olanzapineinducedpancytopeniacasereport |