Olanzapine-induced Pancytopenia: Case Report

In the field of antipsychotic medicines, clozapine and olanzapine are both structurally and functionally similar. This case study describes a 35-year-old man with paranoid schizophrenia who experienced a rare case of olanzapine-induced pancytopenia. The patient required blood transfusions due to sev...

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Bibliographic Details
Main Authors: A Prajnashree, S. K Someshwar, Arfa A Sayed, K P Abhirami, Sanatkumar B. Nyamagoud
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-11-01
Series:Medical Journal of Dr. D.Y. Patil Vidyapeeth
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Online Access:https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_13_24
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Summary:In the field of antipsychotic medicines, clozapine and olanzapine are both structurally and functionally similar. This case study describes a 35-year-old man with paranoid schizophrenia who experienced a rare case of olanzapine-induced pancytopenia. The patient required blood transfusions due to severe pancytopenia while receiving olanzapine treatment. The study emphasizes how crucial it is to acknowledge pancytopenia caused by olanzapine as a rare but significant medication-induced risk. It is recommended that clinicians exercise caution, perform routine hematologic assessments, and participate in ongoing investigations into this rare adverse event. However, sporadic reports of olanzapine-induced pancytopenia in schizophrenia patients have surfaced. This hematologic effect’s precise mechanism is still unknown.
ISSN:2589-8302
2589-8310