Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysis
Introduction Smoking among persons with a mental health disorder is associated with inequitable health, social and economic burden. Randomised controlled trials (RCTs) are considered the gold standard design for the assessment of healthcare intervention efficacy/effectiveness. However, many RCTs of...
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BMJ Publishing Group
2019-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/9/9/e030646.full |
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| author | Luke Wolfenden Gemma Taylor John Wiggers Alexandra Patricia Metse Emily Stockings Jacqueline Bailey Timothy Regan Kate Bartlem Jenny Bowman |
| author_facet | Luke Wolfenden Gemma Taylor John Wiggers Alexandra Patricia Metse Emily Stockings Jacqueline Bailey Timothy Regan Kate Bartlem Jenny Bowman |
| author_sort | Luke Wolfenden |
| collection | DOAJ |
| description | Introduction Smoking among persons with a mental health disorder is associated with inequitable health, social and economic burden. Randomised controlled trials (RCTs) are considered the gold standard design for the assessment of healthcare intervention efficacy/effectiveness. However, many RCTs of smoking interventions for persons with a mental health disorder lack rigour due to low participant retention. No systematic review has pooled retention rates in randomised trials of smoking interventions for persons with a mental health disorder or explored associated factors. The aims of the systematic review will therefore be to: (1) summarise overall rates of participant retention in smoking cessation and reduction trials involving persons with a mental health disorder (including for experimental and control groups separately) and (2) determine if retention rates vary according to participant, environmental, researcher and study factors.Methods and analysis PsycINFO, EMBASE, MEDLINE, CENTRAL and The Cochrane Tobacco Addiction Review Group Specialised Register will be searched for reports of RCTs of outpatient smoking cessation or reduction interventions for adults with a mental health disorder. The search terms will include MeSH terms and free text words, and there will be no language or date restrictions. All databases will be searched from inception to present. Data will be analysed using the Mantel-Haenszel fixed-effect model, and where substantial heterogeneity (I2 >50%) is detected, DerSimonian & Laird inverse-variance random effects model. Pooled estimates and 95% CIs will be calculated for overall participant retention rates and for intervention and control trial arms separately. Associations between participant retention and participant, environmental, researcher and study factors will be assessed via subgroup analyses and, where sufficient data are obtained, meta-regression.Ethics and dissemination This study does not require ethical approval. The findings of this review will be disseminated via publication in a peer-reviewed open access medical journal and presentations at international scientific meetings. |
| format | Article |
| id | doaj-art-527545b031c94d71bc3b6e1397949bc5 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2019-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-527545b031c94d71bc3b6e1397949bc52024-11-29T00:20:13ZengBMJ Publishing GroupBMJ Open2044-60552019-09-019910.1136/bmjopen-2019-030646Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysisLuke Wolfenden0Gemma Taylor1John Wiggers2Alexandra Patricia Metse3Emily Stockings4Jacqueline Bailey5Timothy Regan6Kate Bartlem7Jenny Bowman8School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia8 Addiction and Mental Health Group (AIM) Department of Psychology, University of Bath, Bath, UK5 Hunter New England Population Health, Wallsend, New South Wales, Australia1 School of Psychology, University of Newcastle, Callaghan, New South Wales, AustraliaThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, New South Wales, Australia1 School of Psychology, University of Newcastle, Callaghan, New South Wales, Australia1 School of Psychology, University of Newcastle, Callaghan, New South Wales, Australia1 School of Psychology, University of Newcastle, Callaghan, New South Wales, Australia1 School of Psychology, University of Newcastle, Callaghan, New South Wales, AustraliaIntroduction Smoking among persons with a mental health disorder is associated with inequitable health, social and economic burden. Randomised controlled trials (RCTs) are considered the gold standard design for the assessment of healthcare intervention efficacy/effectiveness. However, many RCTs of smoking interventions for persons with a mental health disorder lack rigour due to low participant retention. No systematic review has pooled retention rates in randomised trials of smoking interventions for persons with a mental health disorder or explored associated factors. The aims of the systematic review will therefore be to: (1) summarise overall rates of participant retention in smoking cessation and reduction trials involving persons with a mental health disorder (including for experimental and control groups separately) and (2) determine if retention rates vary according to participant, environmental, researcher and study factors.Methods and analysis PsycINFO, EMBASE, MEDLINE, CENTRAL and The Cochrane Tobacco Addiction Review Group Specialised Register will be searched for reports of RCTs of outpatient smoking cessation or reduction interventions for adults with a mental health disorder. The search terms will include MeSH terms and free text words, and there will be no language or date restrictions. All databases will be searched from inception to present. Data will be analysed using the Mantel-Haenszel fixed-effect model, and where substantial heterogeneity (I2 >50%) is detected, DerSimonian & Laird inverse-variance random effects model. Pooled estimates and 95% CIs will be calculated for overall participant retention rates and for intervention and control trial arms separately. Associations between participant retention and participant, environmental, researcher and study factors will be assessed via subgroup analyses and, where sufficient data are obtained, meta-regression.Ethics and dissemination This study does not require ethical approval. The findings of this review will be disseminated via publication in a peer-reviewed open access medical journal and presentations at international scientific meetings.https://bmjopen.bmj.com/content/9/9/e030646.full |
| spellingShingle | Luke Wolfenden Gemma Taylor John Wiggers Alexandra Patricia Metse Emily Stockings Jacqueline Bailey Timothy Regan Kate Bartlem Jenny Bowman Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysis BMJ Open |
| title | Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysis |
| title_full | Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysis |
| title_fullStr | Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysis |
| title_full_unstemmed | Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysis |
| title_short | Rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials, and associated factors: protocol for a systematic review and meta-analysis |
| title_sort | rates of retention of persons with a mental health disorder in outpatient smoking cessation and reduction trials and associated factors protocol for a systematic review and meta analysis |
| url | https://bmjopen.bmj.com/content/9/9/e030646.full |
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