PSTK exerts protective role in cisplatin‐tubular cell injury via BAX/BCL2/Caspase3 pathway

PSTK exerts protective role in cisplatin‐tubular cell injury via BAX/BCL2/Caspase3 pathway

Abstract Cisplatin is a widely used anticancer drug, but its accumulation in renal tubular epithelial cells (TECs) can cause acute kidney injury. Phosphoseryl‐tRNA kinase (PSTK) is an intermediate product produced under oxidative stress conditions. This study aimed to elucidate whether PSTK could pr...

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Bibliographic Details
Main Authors: Yifan Wu, Yuanyuan Xv, Limei Zhao, Ziqi Zhou, Miaomiao Wang, Jima Xi, Ying Liming, Jianling Gao, Bingqing Deng, Dong Zheng
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Physiological Reports
Subjects:
AKI
apoptosis
cisplatin
oxidative stress
PSTK
Online Access:https://doi.org/10.14814/phy2.70162
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