Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome
Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a poorly understood, life-threatening multisystemic condition related to pregnancy with a rapid onset, typically observed in patients with severe pre-eclampsia. Various mechanisms may lead to diffuse endothelial damage associat...
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2024-12-01
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| Series: | European Journal of Case Reports in Internal Medicine |
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| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/5019 |
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| _version_ | 1841556086416474112 |
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| author | Rita Pinto Medeiros Maria Ruão Pedro Vita Raquel Monte Aníbal Marinho |
| author_facet | Rita Pinto Medeiros Maria Ruão Pedro Vita Raquel Monte Aníbal Marinho |
| author_sort | Rita Pinto Medeiros |
| collection | DOAJ |
| description | Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a poorly understood, life-threatening multisystemic condition related to pregnancy with a rapid onset, typically observed in patients with severe pre-eclampsia. Various mechanisms may lead to diffuse endothelial damage associated with HELLP and possible brain involvement.
A comprehensive review of PubMed, Embase and Cochrane databases was conducted to examine the clinical, laboratory and radiological features associated with postpartum HELLP syndrome, particularly its potential association with posterior reversible encephalopathy syndrome (PRES). This review was prompted by a rare case we encountered. The literature review identified 10 articles documenting this association during pregnancy and 7 articles reporting it in the postpartum period.
Our patient developed multiple organ dysfunction (renal, hepatic, haemolysis and thrombocytopenia) postpartum associated with an arterial hypertensive profile. The patient experienced seizures along with the maintenance of an arterial hypertensive profile resistant to pharmacological therapy. Brain magnetic resonance imaging allowed the diagnosis of PRES and pituitary adenoma/apoplexy. Follow-up led to complete recovery. |
| format | Article |
| id | doaj-art-5212a1058b91445d89d1738cd746b11b |
| institution | Kabale University |
| issn | 2284-2594 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj-art-5212a1058b91445d89d1738cd746b11b2025-01-07T13:40:28ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942024-12-0110.12890/2024_0050194554Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndromeRita Pinto Medeiros0Maria Ruão1Pedro Vita2Raquel Monte3Aníbal Marinho4Critical Care, Intensive Care Unit, Centro Hospitalar Universitário de Santo António, Porto, PortugalCritical Care, Intensive Care Unit, Centro Hospitalar Universitário de Santo António, Porto, PortugalCritical Care, Intensive Care Unit, Centro Hospitalar Universitário de Santo António, Porto, PortugalCritical Care, Intensive Care Unit, Centro Hospitalar Universitário de Santo António, Porto, PortugalCritical Care, Intensive Care Unit, Centro Hospitalar Universitário de Santo António, Porto, PortugalHaemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a poorly understood, life-threatening multisystemic condition related to pregnancy with a rapid onset, typically observed in patients with severe pre-eclampsia. Various mechanisms may lead to diffuse endothelial damage associated with HELLP and possible brain involvement. A comprehensive review of PubMed, Embase and Cochrane databases was conducted to examine the clinical, laboratory and radiological features associated with postpartum HELLP syndrome, particularly its potential association with posterior reversible encephalopathy syndrome (PRES). This review was prompted by a rare case we encountered. The literature review identified 10 articles documenting this association during pregnancy and 7 articles reporting it in the postpartum period. Our patient developed multiple organ dysfunction (renal, hepatic, haemolysis and thrombocytopenia) postpartum associated with an arterial hypertensive profile. The patient experienced seizures along with the maintenance of an arterial hypertensive profile resistant to pharmacological therapy. Brain magnetic resonance imaging allowed the diagnosis of PRES and pituitary adenoma/apoplexy. Follow-up led to complete recovery.https://www.ejcrim.com/index.php/EJCRIM/article/view/5019haemolysis elevated liver enzymes and low platelets syndromehellpposterior reversible encephalopathy syndromepresobstetric emergencies |
| spellingShingle | Rita Pinto Medeiros Maria Ruão Pedro Vita Raquel Monte Aníbal Marinho Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome European Journal of Case Reports in Internal Medicine haemolysis elevated liver enzymes and low platelets syndrome hellp posterior reversible encephalopathy syndrome pres obstetric emergencies |
| title | Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome |
| title_full | Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome |
| title_fullStr | Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome |
| title_full_unstemmed | Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome |
| title_short | Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome |
| title_sort | postpartum hellp syndrome associated with posterior reversible encephalopathy syndrome |
| topic | haemolysis elevated liver enzymes and low platelets syndrome hellp posterior reversible encephalopathy syndrome pres obstetric emergencies |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/5019 |
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