Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies

AimsMutations in the cardiac ryanodine receptor (RyR2) are associated with catecholaminergic polymorphic ventricular tachycardia (CPVT). This study investigates the underlying molecular mechanisms for CPVT mutations within the RyR2 N-terminus domain (NTD).Methods and ResultsWe consulted the high-res...

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Bibliographic Details
Main Authors: Yadan Zhang, Monika Seidel, Camille Rabesahala de Meritens, Astrid Beckmann, Syeda Ahmed, Melanie Hurtz, F. Anthony Lai, Esther Zorio, Dimitris Parthimos, Spyros Zissimopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1505698/full
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