Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat

The city of Philadelphia has seen an increase in homelessness and substance use disorders, often associated with xylazine-contaminated opiates. Here, we report the first two cases of wound infection and bacteremia associated with the Gram-negative rod Ignatzschineria species. Both cases were associa...

Full description

Saved in:
Bibliographic Details
Main Authors: Erin Pomerantz, Olivia Pericak, Carly Sokach, Jocelyn Edathil, Ho-Man Yeung
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/crdi/7684187
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846118186882170880
author Erin Pomerantz
Olivia Pericak
Carly Sokach
Jocelyn Edathil
Ho-Man Yeung
author_facet Erin Pomerantz
Olivia Pericak
Carly Sokach
Jocelyn Edathil
Ho-Man Yeung
author_sort Erin Pomerantz
collection DOAJ
description The city of Philadelphia has seen an increase in homelessness and substance use disorders, often associated with xylazine-contaminated opiates. Here, we report the first two cases of wound infection and bacteremia associated with the Gram-negative rod Ignatzschineria species. Both cases were associated with maggot colonization in chronic lower extremity wounds from fentanyl/xylazine injections. Poor living conditions and lack of wound care are central to both case presentations. We believe this organism to be an emerging medical threat associated with injection drug use, xylazine-associated wounds, and homelessness which may impact future treatment options in this patient population. This report underscores the emergence of Ignatzschineria bacteremia in individuals with a history of xylazine-associated wounds and substance use disorder. Successful management should prioritize wound care and adherence to antibiotic regimens to prevent complications in these challenging cases.
format Article
id doaj-art-51c57824841f4db69f1133421c0db5fc
institution Kabale University
issn 2090-6633
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series Case Reports in Infectious Diseases
spelling doaj-art-51c57824841f4db69f1133421c0db5fc2024-12-18T05:00:02ZengWileyCase Reports in Infectious Diseases2090-66332024-01-01202410.1155/crdi/7684187Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging ThreatErin Pomerantz0Olivia Pericak1Carly Sokach2Jocelyn Edathil3Ho-Man Yeung4Department of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineDepartment of MedicineThe city of Philadelphia has seen an increase in homelessness and substance use disorders, often associated with xylazine-contaminated opiates. Here, we report the first two cases of wound infection and bacteremia associated with the Gram-negative rod Ignatzschineria species. Both cases were associated with maggot colonization in chronic lower extremity wounds from fentanyl/xylazine injections. Poor living conditions and lack of wound care are central to both case presentations. We believe this organism to be an emerging medical threat associated with injection drug use, xylazine-associated wounds, and homelessness which may impact future treatment options in this patient population. This report underscores the emergence of Ignatzschineria bacteremia in individuals with a history of xylazine-associated wounds and substance use disorder. Successful management should prioritize wound care and adherence to antibiotic regimens to prevent complications in these challenging cases.http://dx.doi.org/10.1155/crdi/7684187
spellingShingle Erin Pomerantz
Olivia Pericak
Carly Sokach
Jocelyn Edathil
Ho-Man Yeung
Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat
Case Reports in Infectious Diseases
title Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat
title_full Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat
title_fullStr Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat
title_full_unstemmed Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat
title_short Two Cases of Maggot-Associated Ignatzschineria Bacteremia in Xylazine-Induced Injection Wounds: An Emerging Threat
title_sort two cases of maggot associated ignatzschineria bacteremia in xylazine induced injection wounds an emerging threat
url http://dx.doi.org/10.1155/crdi/7684187
work_keys_str_mv AT erinpomerantz twocasesofmaggotassociatedignatzschineriabacteremiainxylazineinducedinjectionwoundsanemergingthreat
AT oliviapericak twocasesofmaggotassociatedignatzschineriabacteremiainxylazineinducedinjectionwoundsanemergingthreat
AT carlysokach twocasesofmaggotassociatedignatzschineriabacteremiainxylazineinducedinjectionwoundsanemergingthreat
AT jocelynedathil twocasesofmaggotassociatedignatzschineriabacteremiainxylazineinducedinjectionwoundsanemergingthreat
AT homanyeung twocasesofmaggotassociatedignatzschineriabacteremiainxylazineinducedinjectionwoundsanemergingthreat