Disrupted NAD(P) Metabolism and Xanthine Dehydrogenase in a Stress-Induced Rat Model of Depression: NMR Metabolomics Insights

Disrupted NAD(P) Metabolism and Xanthine Dehydrogenase in a Stress-Induced Rat Model of Depression: NMR Metabolomics Insights

<b>Background</b>: Clinical findings have shown a negative correlation between the severity of depressive symptoms and serum uric acid levels in men, yet the role of metabolic regulation in the pathophysiology of depression remains largely unknown. <b>Methods</b>: In this stu...

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Bibliographic Details
Main Authors:	Songjiao Chen, Jumeng Wei, Yongchi Wang, Yidan Yao, Haibo Wang, Jie Peng, Jinquan Li
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Series:	Metabolites
Subjects:	uric acid NAD(P) deficiency xanthine oxidoreductase untargeted metabolomics rat model of depression
Online Access:	https://www.mdpi.com/2218-1989/14/12/660
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