Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrest

Aim: Guidelines recommend supraglottic airways (e.g. laryngeal tube, LT) for out-of-hospital cardiac arrest (OHCA) if providers are not skilled in endotracheal intubation (ETI). In prolonged cardiopulmonary resuscitation (CPR) LT led to asphyxial physiology. Therefore we evaluated the impact of LT v...

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Main Authors: Olaf Aretz, Jana Vienna Rödler, Athina Gavriil, Marc Deussen, Emmanuel Chorianopoulos, Sebastian Bergrath
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Resuscitation Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666520424002649
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author Olaf Aretz
Jana Vienna Rödler
Athina Gavriil
Marc Deussen
Emmanuel Chorianopoulos
Sebastian Bergrath
author_facet Olaf Aretz
Jana Vienna Rödler
Athina Gavriil
Marc Deussen
Emmanuel Chorianopoulos
Sebastian Bergrath
author_sort Olaf Aretz
collection DOAJ
description Aim: Guidelines recommend supraglottic airways (e.g. laryngeal tube, LT) for out-of-hospital cardiac arrest (OHCA) if providers are not skilled in endotracheal intubation (ETI). In prolonged cardiopulmonary resuscitation (CPR) LT led to asphyxial physiology. Therefore we evaluated the impact of LT vs. ETI on gasometry and lactate at admission. Methods: All patients from 1 January 2020 to 30 April 2023 with return of spontaneous circulation (ROSC) or ongoing CPR (no ROSC) were included in this retrospective cohort study.Continuous data were analysed using the Mann-Whitney-U-Test. Results: Overall, 147 patients were included: ETI, n = 104; LT, n = 33; other airways, n = 10. ROSC, n = 86; no ROSC, n = 61. ETI vs. LT (median) for all patients showed: arterial blood gas analyses (BGA) (n = 62 vs. n = 20): pH 7.01 vs. 7.07, p = 0.83; pCO2 64.5 vs. 66.6 mmHg, p = 0.62; lactate 10.1 vs. 9.5 mmol/l, p = 0.68. Venous BGA (n = 37 vs. n = 11): pH 6.91 vs. 7.12, p = 0.15; pCO2 77.4 vs. 66.0 mmHg, p = 0.19; lactate 11.5 vs. 8.6 mmol/l, p = 0.24. ROSC, arterial BGA (n = 39 vs. n = 12): pH 7.09 vs. 7.14, p = 0.36; pCO2 60.3 vs. 56.4 mmHg, p = 0.84; lactate 8.95 vs. 7.0 mmol/l, p = 0.35. No ROSC, arterial BGA (n = 23 vs. n = 8): pH 6.9 vs. 6.8, p = 0.03; pCO2 80.7 vs. 85.6 mmHg, p = 0.64; lactate 13.0 vs. 14.6 mmol/l, p = 0.62. Conclusion: The prehospital airway strategy had no impact on gasometry in this OHCA collective except a better pH with ETI in no ROSC. Due to small numbers and non-existent data about the exact prehospital ventilation parameters, further prospective studies are needed to evaluate this question.
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spelling doaj-art-519ab749c51a40539dd46dfce8d90e5e2024-12-21T04:29:56ZengElsevierResuscitation Plus2666-52042024-12-0120100813Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrestOlaf Aretz0Jana Vienna Rödler1Athina Gavriil2Marc Deussen3Emmanuel Chorianopoulos4Sebastian Bergrath5Department of Clinical Acute and Emergency Medicine, Kliniken Maria Hilf Mönchengladbach, Academic Teaching Hospital of RWTH Aachen University, Germany; Chair of Anaesthesiology, Medical Faculty of RWTH Aachen University, GermanyDepartment of Clinical Acute and Emergency Medicine, Kliniken Maria Hilf Mönchengladbach, Academic Teaching Hospital of RWTH Aachen University, GermanyDepartment of Cardiology and Internal Intensive Care Medicine, Kliniken Maria Hilf Mönchengladbach, Academic Teaching Hospital of RWTH Aachen University, GermanyEmergency Medical Service and Fire Department of the City of Mönchengladbach, GermanyDepartment of Cardiology and Internal Intensive Care Medicine, Kliniken Maria Hilf Mönchengladbach, Academic Teaching Hospital of RWTH Aachen University, GermanyDepartment of Clinical Acute and Emergency Medicine, Kliniken Maria Hilf Mönchengladbach, Academic Teaching Hospital of RWTH Aachen University, Germany; Chair of Anaesthesiology, Medical Faculty of RWTH Aachen University, Germany; Corresponding author at: Department of Clinical Acute and Emergency Medicine, Kliniken Maria Hilf, Academic Teaching Hospital of RWTH Aachen University, Viersener Straße 450, 41063 Mönchengladbach, Germany.Aim: Guidelines recommend supraglottic airways (e.g. laryngeal tube, LT) for out-of-hospital cardiac arrest (OHCA) if providers are not skilled in endotracheal intubation (ETI). In prolonged cardiopulmonary resuscitation (CPR) LT led to asphyxial physiology. Therefore we evaluated the impact of LT vs. ETI on gasometry and lactate at admission. Methods: All patients from 1 January 2020 to 30 April 2023 with return of spontaneous circulation (ROSC) or ongoing CPR (no ROSC) were included in this retrospective cohort study.Continuous data were analysed using the Mann-Whitney-U-Test. Results: Overall, 147 patients were included: ETI, n = 104; LT, n = 33; other airways, n = 10. ROSC, n = 86; no ROSC, n = 61. ETI vs. LT (median) for all patients showed: arterial blood gas analyses (BGA) (n = 62 vs. n = 20): pH 7.01 vs. 7.07, p = 0.83; pCO2 64.5 vs. 66.6 mmHg, p = 0.62; lactate 10.1 vs. 9.5 mmol/l, p = 0.68. Venous BGA (n = 37 vs. n = 11): pH 6.91 vs. 7.12, p = 0.15; pCO2 77.4 vs. 66.0 mmHg, p = 0.19; lactate 11.5 vs. 8.6 mmol/l, p = 0.24. ROSC, arterial BGA (n = 39 vs. n = 12): pH 7.09 vs. 7.14, p = 0.36; pCO2 60.3 vs. 56.4 mmHg, p = 0.84; lactate 8.95 vs. 7.0 mmol/l, p = 0.35. No ROSC, arterial BGA (n = 23 vs. n = 8): pH 6.9 vs. 6.8, p = 0.03; pCO2 80.7 vs. 85.6 mmHg, p = 0.64; lactate 13.0 vs. 14.6 mmol/l, p = 0.62. Conclusion: The prehospital airway strategy had no impact on gasometry in this OHCA collective except a better pH with ETI in no ROSC. Due to small numbers and non-existent data about the exact prehospital ventilation parameters, further prospective studies are needed to evaluate this question.http://www.sciencedirect.com/science/article/pii/S2666520424002649Out-of-hospital cardiac arrestEndotracheal intubationLaryngeal tubeGasometryPhysiology
spellingShingle Olaf Aretz
Jana Vienna Rödler
Athina Gavriil
Marc Deussen
Emmanuel Chorianopoulos
Sebastian Bergrath
Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrest
Resuscitation Plus
Out-of-hospital cardiac arrest
Endotracheal intubation
Laryngeal tube
Gasometry
Physiology
title Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrest
title_full Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrest
title_fullStr Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrest
title_full_unstemmed Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrest
title_short Impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out-of-hospital cardiac arrest
title_sort impact of endotracheal intubation versus laryngeal tube on gasometry and lactate at emergency department admission after out of hospital cardiac arrest
topic Out-of-hospital cardiac arrest
Endotracheal intubation
Laryngeal tube
Gasometry
Physiology
url http://www.sciencedirect.com/science/article/pii/S2666520424002649
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