KEAP1–NRF2 system regulates age‐related spermatogenesis dysfunction

KEAP1–NRF2 system regulates age‐related spermatogenesis dysfunction

Abstract Purpose The average fatherhood age has been consistently increasing in developed countries. Aging has been identified as a risk factor for male infertility. However, its impact on various mechanisms remains unclear. This study focused on the KEAP1–NRF2 oxidative stress response system, by i...

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Main Authors: Sohei Kuribayashi, Shinichiro Fukuhara, Hiroaki Kitakaze, Go Tsujimura, Takahiro Imanaka, Koichi Okada, Norichika Ueda, Kentaro Takezawa, Kotoe Katayama, Rui Yamaguchi, Koichi Matsuda, Norio Nonomura
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Reproductive Medicine and Biology
Subjects:
aging
KEAP1–NRF2
male infertility
oxidative stress
Online Access:https://doi.org/10.1002/rmb2.12595
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