Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report
Purpose: Keloid tissue represents an abnormal proliferation of fibroblasts, typically resulting from skin injury. These lesions can lead to significant physiological dysfunction and aesthetic concerns, particularly when located on the face. Traditional treatments, such as intralesional injections, l...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/09546634.2025.2451394 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841542612186562560 |
|---|---|
| author | Xianghui Li Yong Wei Zhuren Ruan Gao Wei Zhijian Yao |
| author_facet | Xianghui Li Yong Wei Zhuren Ruan Gao Wei Zhijian Yao |
| author_sort | Xianghui Li |
| collection | DOAJ |
| description | Purpose: Keloid tissue represents an abnormal proliferation of fibroblasts, typically resulting from skin injury. These lesions can lead to significant physiological dysfunction and aesthetic concerns, particularly when located on the face. Traditional treatments, such as intralesional injections, laser therapy, and surgical excision, have shown limited efficacy and are associated with high recurrence rates.Materials and methods: In a recent case, a 19-year-old male with a keloid on the upper lip did not respond to local injections of triamcinolone acetonide (TAC) or carbon dioxide ablative fractional resurfacing laser therapy.Results: A combined treatment approach involving trepanation and superficial radiotherapy successfully flattened the keloid tissue, with no recurrence observed during a 3-year follow-up period.Conclusions: This case underscores the potential efficiency and safety of combined therapeutic interventions and contributes valuable evidence towards the development of novel treatment strategies for keloids. |
| format | Article |
| id | doaj-art-516850f18f054fd0bc1064ca3ba0b4d4 |
| institution | Kabale University |
| issn | 0954-6634 1471-1753 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj-art-516850f18f054fd0bc1064ca3ba0b4d42025-01-13T23:15:00ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532025-12-0136110.1080/09546634.2025.2451394Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case reportXianghui Li0Yong Wei1Zhuren Ruan2Gao Wei3Zhijian Yao4Department of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Dermatology and Venereology, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaPurpose: Keloid tissue represents an abnormal proliferation of fibroblasts, typically resulting from skin injury. These lesions can lead to significant physiological dysfunction and aesthetic concerns, particularly when located on the face. Traditional treatments, such as intralesional injections, laser therapy, and surgical excision, have shown limited efficacy and are associated with high recurrence rates.Materials and methods: In a recent case, a 19-year-old male with a keloid on the upper lip did not respond to local injections of triamcinolone acetonide (TAC) or carbon dioxide ablative fractional resurfacing laser therapy.Results: A combined treatment approach involving trepanation and superficial radiotherapy successfully flattened the keloid tissue, with no recurrence observed during a 3-year follow-up period.Conclusions: This case underscores the potential efficiency and safety of combined therapeutic interventions and contributes valuable evidence towards the development of novel treatment strategies for keloids.https://www.tandfonline.com/doi/10.1080/09546634.2025.2451394Keloidtrepanationradiotherapyupper lip |
| spellingShingle | Xianghui Li Yong Wei Zhuren Ruan Gao Wei Zhijian Yao Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report Journal of Dermatological Treatment Keloid trepanation radiotherapy upper lip |
| title | Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report |
| title_full | Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report |
| title_fullStr | Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report |
| title_full_unstemmed | Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report |
| title_short | Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report |
| title_sort | successful treatment of a keloid on the upper lip by trepanation and radiotherapy a case report |
| topic | Keloid trepanation radiotherapy upper lip |
| url | https://www.tandfonline.com/doi/10.1080/09546634.2025.2451394 |
| work_keys_str_mv | AT xianghuili successfultreatmentofakeloidontheupperlipbytrepanationandradiotherapyacasereport AT yongwei successfultreatmentofakeloidontheupperlipbytrepanationandradiotherapyacasereport AT zhurenruan successfultreatmentofakeloidontheupperlipbytrepanationandradiotherapyacasereport AT gaowei successfultreatmentofakeloidontheupperlipbytrepanationandradiotherapyacasereport AT zhijianyao successfultreatmentofakeloidontheupperlipbytrepanationandradiotherapyacasereport |