Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis

Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis

The purpose of this study was to investigate the role of oncostatin M (OSM) in tubulointerstitial lesion (TIL) in lupus nephritis (LN). We found that OSM was highly expressed in the renal tissue of LN mice. OSM is one of the interleukin-6 cytokine family members. In order to clarify the role and mec...

Full description

Saved in:

Bibliographic Details
Main Authors:	Qingjuan Liu, Yunxia Du, Kejun Li, Wei Zhang, Xiaojuan Feng, Jun Hao, Hongbo Li, Shuxia Liu
Format:	Article
Language:	English
Published:	Wiley 2017-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2017/3038514
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Tubulointerstitial nephritis in cases of lupus nephritis: An experience from a tertiary care referral center of Eastern India
by: Keya Basu, et al.
Published: (2022-09-01)

Case report and literature review: IgG4-related tubulointerstitial nephritis coexistent with systemic lupus erythematosus
by: Xingfu Ji, et al.
Published: (2025-07-01)

Tubulointerstitial nephritis and uveitis (TINU) syndrome: a case series
by: Richard Farnan, et al.
Published: (2025-07-01)

Tubulointerstitial Nephritis and Uveitis Syndrome: Case Series and Literature Review
by: Beatriz Oliveira Lopes, et al.
Published: (2021-01-01)

WCN24-1872 Uncommon Manifestation of Primary Sjögren's Syndrome: Granulomatous Tubulointerstitial Nephritis
by: FRECIA CASTRO, et al.
Published: (2024-04-01)

Effect of renal interstitial vascular lesions on clinical pathological features and outcomes of lupus nephritis
by: HU Ai-xia, et al.
Published: (2019-01-01)

Recent advances in the treatment of lupus nephritis
by: Wan-xing Li, et al.
Published: (2022-08-01)

The Evolution of Crescents in Lupus Nephritis
by: Ana Malvar, et al.
Published: (2025-05-01)

Gender Differences in the Pathogenesis and Outcome of Lupus and of Lupus Nephritis
by: Julie Schwartzman-Morris, et al.
Published: (2012-01-01)

USE OF RITUXIMAB IN PATIENTS WITH LUPUS NEPHRITIS
by: Anna Vasilyevna Torgashina, et al.
Published: (2010-08-01)

Prospects for the use of belimumab in lupus nephritis
by: N. L. Kozlovskaya, et al.
Published: (2021-08-01)

WCN24-743 BLIND SPOT IN THE RADAR OF MEST-C SCORE: TYPE AND SEVERITY OF TUBULOINTERSTITIAL NEPHRITIS IN IGA NEPHROPATHY
by: Aurangzeb Afzal, et al.
Published: (2024-04-01)

Immuno-morphological features of glomerular and tubulointerstitial kidney damage in patients with systemic lupus erythematosus
by: N A Arzimanova, et al.
Published: (2009-04-01)

Chemokines and Chemokine Receptors in the Development of Lupus Nephritis
by: Xiaofeng Liao, et al.
Published: (2016-01-01)

Immune Checkpoint Therapy–Induced Lupus Nephritis
by: Imran Humza Hanif, et al.
Published: (2024-05-01)

Efficacy and safety of telitacicept in systemic lupus erythematosus with lupus nephritis and nephrotic syndrome: a 12-month retrospective cohort study
by: Min-Ying Liu, et al.
Published: (2025-07-01)

Comparison of Pregnancy Outcomes between Lupus Nephritis Patients and Nonlupus Nephritis Systemic Lupus Erythematosus Patients at a Tertiary Care Center in Mumbai
by: Preeti Mehta Nagnur, et al.
Published: (2025-01-01)

Sirt1 protects lupus nephritis by inhibiting the NLRP3 signaling pathway in human glomerular mesangial cells
by: Zhao Yu, et al.
Published: (2025-04-01)

Lupus nephritis. Part II, modern ideas about therapy
by: Elena A. Aseeva, et al.
Published: (2024-09-01)

Programmed immunoadsorption with regeneration of adsoption columns in the treatment of lupus nephritis
by: A. A. Sokolov, et al.
Published: (2020-09-01)

WCN25-1700 SHORT TERM OUTCOMES OF LUPUS NEPHRITIS
by: VIJAYADURAIRAJ KOTTURSAMY, et al.
Published: (2025-02-01)

Lupus nephritis – modern aspects of diagnosis and therapy. Part I
by: S. K. Solovyev, et al.
Published: (2024-03-01)

Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
by: Bancha Satirapoj, et al.
Published: (2015-01-01)

Interleukin biomarkers as predictive tools for lupus nephritis grade and disease activity in systemic lupus erythematosus
by: Dalia S. Saif, et al.
Published: (2025-04-01)

The Involvement of MicroRNAs in Modulation of Innate and Adaptive Immunity in Systemic Lupus Erythematosus and Lupus Nephritis
by: Mohsen Honarpisheh, et al.
Published: (2018-01-01)

Autophagy in patients with lupus nephritis and its effect on podocyte related protein expression
by: LI Zhang-hong, et al.
Published: (2020-01-01)

Clinical observation of different ways of blood purification combined with immune inhibitors for the treatment of serious lupus nephritis
by: LIU Lei, et al.
Published: (2017-01-01)

A Rare Case of Severe Skin Reaction to Mycophenolate Mofetil in Systemic Lupus Erythematosus with Lupus Nephritis
by: Rubiya M, et al.
Published: (2025-01-01)

2024 ACR guidelines on screening, treatment, and management of patients with lupus nephritis
by: E. A. Aseeva, et al.
Published: (2025-06-01)

Relationship between macrophage phenotype and kidney survival in patients with lupus nephritis
by: Ozcan Uzun, et al.
Published: (2025-06-01)

Dysregulation of miR-155-5p and miR-200-3p and the Anti-Non-Bilayer Phospholipid Arrangement Antibodies Favor the Development of Lupus in Three Novel Murine Lupus Models
by: Luz Ángela Zárate-Neira, et al.
Published: (2017-01-01)

The Efficacy and Safety of Leflunomide for the Treatment of Lupus Nephritis in Chinese Patients: Systematic Review and Meta-Analysis.
by: Heng Cao, et al.
Published: (2015-01-01)

Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis
by: ZHANG Xian-qin, et al.
Published: (2018-01-01)

Strongyloides stercoralis Presenting as Diffuse Alveolar Hemorrhage in a Lupus Nephritis Patient
by: Rojashree Gundu, et al.
Published: (2023-01-01)

Podocyte extracellular vesicles and immune mediators as urinary biomarkers in active lupus nephritis
by: Lilian Alves, et al.
Published: (2025-08-01)

Case Report: Full-house renal-limited lupus-like nephritis in pregnancy
by: Lucille Jane Wilkinson, et al.
Published: (2025-06-01)

Lupus nephritis and U1-RNP-antibodies are associated with low bone mineral density and osteoporosis in patients with systemic lupus erythematosus: baseline findings in a sub-cohort of patients with inflammatory rheumatic diseases
by: Edgar Wiebe, et al.
Published: (2025-07-01)

Serum Interleukin-23 in Polish Patients with Systemic Lupus Erythematosus: Association with Lupus Nephritis, Obesity, and Peripheral Vascular Disease
by: Katarzyna Fischer, et al.
Published: (2017-01-01)

Lupus nephritis association with idiopathic CD4 + T lymphocytopenia: a case report of a young man with recalcitrant warts
by: Tingting Wang, et al.
Published: (2025-07-01)

Tuberous Sclerosis Complex–Associated Tubulointerstitial Kidney Disease
by: Hamza Sakhi, et al.
Published: (2025-06-01)