Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria

Background. Rhesus antigens have been documented to cause haemolytic disease of the newborn as well as acute and delayed transfusion reactions. This study was performed to evaluate the frequency of rhesus antigens (C, c, D, E, and e) in the studied population. Method. This study was a cross-sectiona...

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Main Authors: Joyce Ezekiel Etura, Rose A. Amaechi, Josephine O. Akpotuzor, Henshaw Uchechi Okoroiwu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2020/2659398
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author Joyce Ezekiel Etura
Rose A. Amaechi
Josephine O. Akpotuzor
Henshaw Uchechi Okoroiwu
author_facet Joyce Ezekiel Etura
Rose A. Amaechi
Josephine O. Akpotuzor
Henshaw Uchechi Okoroiwu
author_sort Joyce Ezekiel Etura
collection DOAJ
description Background. Rhesus antigens have been documented to cause haemolytic disease of the newborn as well as acute and delayed transfusion reactions. This study was performed to evaluate the frequency of rhesus antigens (C, c, D, E, and e) in the studied population. Method. This study was a cross-sectional study involving 130 prospective blood donors attending University of Calabar Teaching Hospital (UCTH) donor clinic. Donors were grouped for Rh antisera (anti-E, anti-e, anti-C, anti-c, and anti-D) using the standard serologic technique. Result. The most prevalent Rh antigen was “c” (98.5%), followed by “D” (97.7%), while the least was “C” (30.7%). The most prevalent phenotype was cDe/cDe (R0R0). Conclusion. This work therefore concludes that the most prevalent rhesus antigen and rhesus phenotype was c and cDe/cDe among blood donors in University of Calabar Teaching Hospital.
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series Advances in Hematology
spelling doaj-art-515d3a3f01c14ea59cc62b51b90d40d12025-08-20T03:36:38ZengWileyAdvances in Hematology1687-91041687-91122020-01-01202010.1155/2020/26593982659398Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, NigeriaJoyce Ezekiel Etura0Rose A. Amaechi1Josephine O. Akpotuzor2Henshaw Uchechi Okoroiwu3Haematology Unit, Department of Medical Laboratory Science, University of Calabar, Calabar, NigeriaHaematology Unit, Department of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo State, NigeriaHaematology Unit, Department of Medical Laboratory Science, University of Calabar, Calabar, NigeriaHaematology Unit, Department of Medical Laboratory Science, University of Calabar, Calabar, NigeriaBackground. Rhesus antigens have been documented to cause haemolytic disease of the newborn as well as acute and delayed transfusion reactions. This study was performed to evaluate the frequency of rhesus antigens (C, c, D, E, and e) in the studied population. Method. This study was a cross-sectional study involving 130 prospective blood donors attending University of Calabar Teaching Hospital (UCTH) donor clinic. Donors were grouped for Rh antisera (anti-E, anti-e, anti-C, anti-c, and anti-D) using the standard serologic technique. Result. The most prevalent Rh antigen was “c” (98.5%), followed by “D” (97.7%), while the least was “C” (30.7%). The most prevalent phenotype was cDe/cDe (R0R0). Conclusion. This work therefore concludes that the most prevalent rhesus antigen and rhesus phenotype was c and cDe/cDe among blood donors in University of Calabar Teaching Hospital.http://dx.doi.org/10.1155/2020/2659398
spellingShingle Joyce Ezekiel Etura
Rose A. Amaechi
Josephine O. Akpotuzor
Henshaw Uchechi Okoroiwu
Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria
Advances in Hematology
title Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria
title_full Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria
title_fullStr Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria
title_full_unstemmed Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria
title_short Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria
title_sort demographics of rhesus phenotype of blood donors in calabar a case study of university of calabar teaching hospital calabar cross river state nigeria
url http://dx.doi.org/10.1155/2020/2659398
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