The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017
Objectives: This study used the Disability-Adjusted Life Years (DALYs) to quantify the long-term trends for four cancers (oral cancer, colorectal cancer, breast cancer, and cervical cancer) that have undergone cancer screening in Taiwan. Methods: DALYs were calculated as the sum of Years of Life Los...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025000660 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841533302186442752 |
|---|---|
| author | Chun-Hui Lin Cheng-Chieh Hsieh Si-Yu Chen Hong-Ru Chen Szu-Chieh Chen |
| author_facet | Chun-Hui Lin Cheng-Chieh Hsieh Si-Yu Chen Hong-Ru Chen Szu-Chieh Chen |
| author_sort | Chun-Hui Lin |
| collection | DOAJ |
| description | Objectives: This study used the Disability-Adjusted Life Years (DALYs) to quantify the long-term trends for four cancers (oral cancer, colorectal cancer, breast cancer, and cervical cancer) that have undergone cancer screening in Taiwan. Methods: DALYs were calculated as the sum of Years of Life Lost (YLL) due to premature mortality and Years Lived with Disability (YLD). YLLs were determined using cancer-specific mortality data from the Health Promotion Administration (HPA), Ministry of Health and Welfare, based on age-specific life expectancy. YLDs were estimated by combining the incidence rates of the cancers, average disability durations, and disability weights, with data sourced from the Taiwan Cancer Registry. Results were expressed as DALYs per 100,000 population. Results: The disease burden has significantly increased over the past 12 years. Oral cancer rose from 263 to 368 DALYs per 100,000 population (40 % increase), colorectal cancer from 343 to 563 DALYs (64 % increase), and breast cancer from 446 to 782 DALYs (75 % increase), while the burden of cervical cancer decreased from 168 to 147 DALYs per 100,000 population from 2010 to 2017, showing a 13 % reduction. At the cancer stages, the impact of YLDs was mostly at cancer stage IV (oral cancer), cancer stage 0 (colorectal and cervical cancer), and stage I (breast cancer). Conclusion: Oral cancer increased by 40 %, colorectal cancer by 64 %, and breast cancer by 75 % from 2005 to 2017, while cervical cancer decreased by 13 % between 2010 and 2017. YLD contributions were highest in stage IV for oral cancer, stage 0 for colorectal and cervical cancers, and stage I for breast cancer. The highest DALYs consistently occurred in the 50–69 age group across all cancer types, highlighting the significant burden on middle-aged populations. |
| format | Article |
| id | doaj-art-51151b0045dd4a76b8b491948d8060bc |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-51151b0045dd4a76b8b491948d8060bc2025-01-17T04:51:55ZengElsevierHeliyon2405-84402025-01-01111e41686The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017Chun-Hui Lin0Cheng-Chieh Hsieh1Si-Yu Chen2Hong-Ru Chen3Szu-Chieh Chen4Department of Public Health, Chung Shan Medical University, Taichung, 40201, Taiwan; Department of Surgery, Division of General Surgery, Feng Yuan Hospital, Ministry of Health and Welfare, Taichung, 42055, TaiwanDepartment of Public Health, Chung Shan Medical University, Taichung, 40201, TaiwanDepartment of Bioenvironmental Systems Engineering, National Taiwan University, Taipei, 10617, TaiwanDepartment of Public Health, Chung Shan Medical University, Taichung, 40201, TaiwanDepartment of Public Health, Chung Shan Medical University, Taichung, 40201, Taiwan; Department of Family and Community Medicine, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan; Corresponding author. Department of Public Health, Chung Shan Medical University, No. 110, Sec. 1, Juanguo N. Rd., Taichung City, 40201, Taiwan.Objectives: This study used the Disability-Adjusted Life Years (DALYs) to quantify the long-term trends for four cancers (oral cancer, colorectal cancer, breast cancer, and cervical cancer) that have undergone cancer screening in Taiwan. Methods: DALYs were calculated as the sum of Years of Life Lost (YLL) due to premature mortality and Years Lived with Disability (YLD). YLLs were determined using cancer-specific mortality data from the Health Promotion Administration (HPA), Ministry of Health and Welfare, based on age-specific life expectancy. YLDs were estimated by combining the incidence rates of the cancers, average disability durations, and disability weights, with data sourced from the Taiwan Cancer Registry. Results were expressed as DALYs per 100,000 population. Results: The disease burden has significantly increased over the past 12 years. Oral cancer rose from 263 to 368 DALYs per 100,000 population (40 % increase), colorectal cancer from 343 to 563 DALYs (64 % increase), and breast cancer from 446 to 782 DALYs (75 % increase), while the burden of cervical cancer decreased from 168 to 147 DALYs per 100,000 population from 2010 to 2017, showing a 13 % reduction. At the cancer stages, the impact of YLDs was mostly at cancer stage IV (oral cancer), cancer stage 0 (colorectal and cervical cancer), and stage I (breast cancer). Conclusion: Oral cancer increased by 40 %, colorectal cancer by 64 %, and breast cancer by 75 % from 2005 to 2017, while cervical cancer decreased by 13 % between 2010 and 2017. YLD contributions were highest in stage IV for oral cancer, stage 0 for colorectal and cervical cancers, and stage I for breast cancer. The highest DALYs consistently occurred in the 50–69 age group across all cancer types, highlighting the significant burden on middle-aged populations.http://www.sciencedirect.com/science/article/pii/S2405844025000660TaiwanCancerMortalityIncidencePublic healthDisease burden |
| spellingShingle | Chun-Hui Lin Cheng-Chieh Hsieh Si-Yu Chen Hong-Ru Chen Szu-Chieh Chen The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017 Heliyon Taiwan Cancer Mortality Incidence Public health Disease burden |
| title | The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017 |
| title_full | The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017 |
| title_fullStr | The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017 |
| title_full_unstemmed | The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017 |
| title_short | The trend of DALY of breast, colorectal, oral, and cervical cancers in Taiwan in 2005–2017 |
| title_sort | trend of daly of breast colorectal oral and cervical cancers in taiwan in 2005 2017 |
| topic | Taiwan Cancer Mortality Incidence Public health Disease burden |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025000660 |
| work_keys_str_mv | AT chunhuilin thetrendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT chengchiehhsieh thetrendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT siyuchen thetrendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT hongruchen thetrendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT szuchiehchen thetrendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT chunhuilin trendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT chengchiehhsieh trendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT siyuchen trendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT hongruchen trendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 AT szuchiehchen trendofdalyofbreastcolorectaloralandcervicalcancersintaiwanin20052017 |