Specific types of male infertility are correlated with T cell exhaustion or senescence signatures
Abstract The association between male infertility and health status has yet to be unraveled. Here, by combining multiparameter phenotyping and scRNA-seq, we delineate the immune status of infertile men both at the semen and systemic levels. We first observe that young infertile men have a pro-inflam...
Saved in:
Main Authors: | Giada Amodio, Giorgia Giacomini, Luca Boeri, Massimiliano Raffo, Simone Cilio, Edoardo Pozzi, Federico Belladelli, Fausto Negri, Anna Maria Ferrara, Alessia d’Arma, Francesca Romana Santoni de Sio, Luca Pagliardini, Enrico Papaleo, Eugenio Ventimiglia, Massimo Alfano, Francesco Montorsi, Andrea Salonia, Silvia Gregori |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-025-56193-2 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Importance of Discordant Follicle Stimulating Hormone and Inhibin B Levels in Primary Infertile Men: Findings from a Cross-Sectional Study
by: Fausto Negri, et al.
Published: (2025-01-01) -
El derecho al consentimiento libre, previo e informado en el Fondo Verde para el Clima: el caso de la implementación de un proyecto en el Datém del Marañón, Perú
by: Giada Giacomini
Published: (2024-06-01) -
HLA-G Expression on Blasts and Tolerogenic Cells in Patients Affected by Acute Myeloid Leukemia
by: Grazia Locafaro, et al.
Published: (2014-01-01) -
Marginal Uncertainties Making a Living and Working on the Outskirts of Milan
by: Giacomo Pozzi, et al.
Published: (2017-07-01) -
Nonlocal order parameter of pair superfluids
by: Nitya Cuzzuol, Luca Barbiero, Arianna Montorsi
Published: (2025-02-01)